Chemical composition and biological activities of essential oil and extracts from Ocimum sanctum
文献类型：期刊论文
| 作者 | Kamal, Ghulam Mustafa1,5; Chatha, Shahzad Ali Shahid3; Hussain, Abdullah Ijaz3; Lazhari, Muhammad Ibrahim4; Hanif, Muhammad Asif2; Ali, Muhammad Adnan3 |
| 刊名 | INTERNATIONAL JOURNAL OF FOOD PROPERTIES
 |
| 出版日期 | 2017 |
| 卷号 | 20期号:7页码:1569-1581 |
| 关键词 | Haem Biocrystallization Assay Gc-ms Antimicrobial Activity Antioxidant Activity Dpph Radical Scavenging Activity |
| DOI | 10.1080/10942912.2016.1214145 |
| 文献子类 | Article |
| 英文摘要 | The objective of the present research work was to evaluate the antioxidant, antimicrobial and antimalarial activities of essential oil and various extracts from O. sanctum. Gas chromatography-mass spectrometry analysis identified the following major compounds with their quantification as: eugenol (22.0%), -elemene (19.2%), -caryophyllene (19.1%), and Germacrene D (5.03%). HPLC analysis of O. sanctum extracts revealed that gallic acid, chlorogenic acid, p-hydroxy benzoic acid, caffeic acid, vanillic acid, p-coumeric acid, sinapic acid, and ferulic acid were the important phenolic acids. The methanol extract exhibited highest level of total phenolic (1.36 g/100 g dry plant material) and total flavonoid (0.67 g/100 g dry plant material) followed by ethanol and n-hexane extracts. The oil and extracts exhibited excellent free radical scavenging potential as measured by 2,2-diphenyl-1-picrylhydrazyl radical free radical-scavenging ability, and antioxidant activity as measured by inhibition of linoleic acid oxidation. Essential oil, n-hexane, methanol, and ethanol extracts exhibited moderate antimalarial potential in term of anti-haem biocrystallization activity. In the resazurin microtitre plate and disc diffusion assays, the essential oil of O. sanctum showed better antibacterial activity than various extracts. The results of the present investigation demonstrated significant (p < 0.05) variations in the antioxidant, antimicrobial, and antimalarial activities of essential oil and extracts from O. sanctum. |
| WOS关键词 | ANTIMICROBIAL ACTIVITY ; ANTIOXIDANT PROPERTIES ; L. ; CONSTITUENTS ; MEMBRANE ; PROFILE ; HEME |
| WOS研究方向 | Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000400459900013 |
| 资助机构 | Higher Education Commision (HEC), Islamabad, Pakistan(20-1584/RD/09/2167) ; Higher Education Commision (HEC), Islamabad, Pakistan(20-1584/RD/09/2167) ; Higher Education Commision (HEC), Islamabad, Pakistan(20-1584/RD/09/2167) ; Higher Education Commision (HEC), Islamabad, Pakistan(20-1584/RD/09/2167) |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/11447]  |
| 专题 | 武汉物理与数学研究所_磁共振基础研究部 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing, Peoples R China 2.Univ Agr Faisalabad, Dept Chem & Biochem, Faisalabad, Pakistan 3.Govt Coll Univ, Dept Appl Chem & Biochem, Nat Prod & Synthet Chem Lab, Faisalabad 38040, Pakistan 4.Univ Sains Malaysia, Sch Pharmaceut Sci, George Town, Malaysia 5.Chinese Acad Sci, Wuhan Inst Phys & Math, Ctr Magnet Resonance, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Kamal, Ghulam Mustafa,Chatha, Shahzad Ali Shahid,Hussain, Abdullah Ijaz,et al. Chemical composition and biological activities of essential oil and extracts from Ocimum sanctum[J]. INTERNATIONAL JOURNAL OF FOOD PROPERTIES,2017,20(7):1569-1581. |
| APA | Kamal, Ghulam Mustafa,Chatha, Shahzad Ali Shahid,Hussain, Abdullah Ijaz,Lazhari, Muhammad Ibrahim,Hanif, Muhammad Asif,&Ali, Muhammad Adnan.(2017).Chemical composition and biological activities of essential oil and extracts from Ocimum sanctum.INTERNATIONAL JOURNAL OF FOOD PROPERTIES,20(7),1569-1581. |
| MLA | Kamal, Ghulam Mustafa,et al."Chemical composition and biological activities of essential oil and extracts from Ocimum sanctum".INTERNATIONAL JOURNAL OF FOOD PROPERTIES 20.7(2017):1569-1581. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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