Quantitative comparison of lung physiological parameters in single and multiple breathhold with hyperpolarized xenon magnetic resonance
文献类型：期刊论文
| 作者 | Liu,Shiyuan1; Zhang,Zhiying2; Guan,Yu1; Li,Haidong2; Zhao,Xiuchao2; Han,Yeqing2; Ye,Chaohui2; Xia,Yi1; Zhou,Xin2; Sun,Xianping2 |
| 刊名 | Biomedical Physics & Engineering Express
 |
| 出版日期 | 2016-09-21 |
| 卷号 | 2期号:5 |
| 关键词 | hyperpolarized gas imaging MRI 129Xe lung chemical shifit saturation recovery 87.61.-c |
| ISSN号 | 2057-1976 |
| DOI | 10.1088/2057-1976/2/5/055013 |
| 英文摘要 | Abstract Hyperpolarized (HP) xenon MR has been an important tool for quantifying the pulmonary structure and gaining functional information by measuring the dynamics of xenon in different lung components, e.g., gas exchange between gaseous xenon in the alveoli and dissolved xenon in tissue/plasma? and red blood cells. Chemical shift saturation recovery is a commonly used pulse sequence to measure the xenon dynamics in the lung globally. However, the effect of the dissolved xenon signal oscillation caused by the cardiac cycle on the physiological parameters of the lung is still unclear. In this study, both single-breathhold (SB) and multiple-breathhold (MB) measurements were used to evaluate these effects in rats, and the data acquired with the MB measurement, which did not have oscillations, served as a reference. The pulmonary physiological parameters were extracted using the model of xenon exchange. The results showed that the physiological parameters derived from SB and MB measurements were not significantly different. These findings have clarified a previously unknown issue and will further promote the design of faster real-time acquisition sequences to quantify structural and functional information about the lung. |
| 语种 | 英语 |
| WOS记录号 | IOP:2057-1976-2-5-055013 |
| 出版者 | IOP Publishing |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/12212]  |
| 专题 | 中国科学院武汉物理与数学研究所 |
| 作者单位 | 1.Department of Radiology, Changzheng Hospital of the Second Military Medical University, Shanghai 200003, People’s Republic of China 2.Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Liu,Shiyuan,Zhang,Zhiying,Guan,Yu,et al. Quantitative comparison of lung physiological parameters in single and multiple breathhold with hyperpolarized xenon magnetic resonance[J]. Biomedical Physics & Engineering Express,2016,2(5). |
| APA | Liu,Shiyuan.,Zhang,Zhiying.,Guan,Yu.,Li,Haidong.,Zhao,Xiuchao.,...&Sun,Xianping.(2016).Quantitative comparison of lung physiological parameters in single and multiple breathhold with hyperpolarized xenon magnetic resonance.Biomedical Physics & Engineering Express,2(5). |
| MLA | Liu,Shiyuan,et al."Quantitative comparison of lung physiological parameters in single and multiple breathhold with hyperpolarized xenon magnetic resonance".Biomedical Physics & Engineering Express 2.5(2016). |
入库方式： OAI收割
来源：武汉物理与数学研究所
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