Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression
文献类型：期刊论文
| 作者 | Zhang, Rubing1,2 ; Cao, Yujin1; Liu, Wei1; Xian, Mo1; Liu, Huizhou1
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| 刊名 | MICROBIAL CELL FACTORIES
 |
| 出版日期 | 2017-12-19 |
| 卷号 | 16 |
| 关键词 | Groesl Expression Level Tolerance Escherichia Coli Phloroglucinol |
| ISSN号 | 1475-2859 |
| DOI | 10.1186/s12934-017-0839-x |
| 文献子类 | Article |
| 英文摘要 | Background: Phloroglucinol is an important chemical which has been successfully produced by engineered Escherichia coli. However, the toxicity of phloroglucinol can enormously inhibit E. coli cell growth and viability, and the productivity is still too low and not economically feasible for industrial applications. Therefore, strain tolerance to toxic metabolites remains a key issue during the production of chemicals using biological processes. |
| WOS关键词 | CLOSTRIDIUM-ACETOBUTYLICUM ; TRANSCRIPTIONAL ANALYSIS ; DIRECTED EVOLUTION ; SOLVENT TOLERANCE ; ACID TOLERANCE ; CHEMICALS ; BUTANOL ; STRESS ; MECHANISMS ; CHAPERONES |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000418667400001 |
| 出版者 | BIOMED CENTRAL LTD |
| 资助机构 | National Natural Science Foundation of China(21572242) ; Taishan Scholars Climbing Program of Shandong(tspd20150210) |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/10493]  |
| 专题 | 中国科学院青岛生物能源与过程研究所 |
| 通讯作者 | Xian, Mo; Liu, Huizhou |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Rubing,Cao, Yujin,Liu, Wei,et al. Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression[J]. MICROBIAL CELL FACTORIES,2017,16. |
| APA | Zhang, Rubing,Cao, Yujin,Liu, Wei,Xian, Mo,&Liu, Huizhou.(2017).Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression.MICROBIAL CELL FACTORIES,16. |
| MLA | Zhang, Rubing,et al."Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression".MICROBIAL CELL FACTORIES 16(2017). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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