Biosynthesis and production of sabinene: current state and perspectives
文献类型：期刊论文
| 作者 | Cao, Yujin; Zhang, Haibo; Liu, Hui; Liu, Wei; Zhang, Rubing; Xian, Mo ; Liu, Huizhou
|
| 刊名 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
 |
| 出版日期 | 2018-02-01 |
| 卷号 | 102期号:4页码:1535-1544 |
| ISSN号 | 0175-7598 |
| 关键词 | Sabinene Terpene Biosynthetic Pathway Sabinene Synthase Microbial Production |
| DOI | 10.1007/s00253-017-8695-5 |
| 文献子类 | Review |
| 英文摘要 | Sabinene is an important naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Up to now, this valuable terpene is commercially unavailable since there is no applicable manufacturing process. Microbial synthesis can be a promising route for sabinene production. In this review, we summarize knowledge about the metabolic pathway and key enzymes for sabinene biosynthesis. Recent advances that have been made in production of sabinene by microbial fermentation are highlighted. In these studies, researchers have identified the general synthetic pathway of sabinene from simple intermediate metabolites. Sabinene synthases of different origins were also cloned and characterized. Additionally, heterologous systems of the model microbes Escherichia coli and Saccharomyces cerevisiae were constructed to produce sabinene. This review also suggests new directions and attempts to gain some insights for achieving an industrial level production of sabinene. The combination of traditional molecular biology with new genome and proteome analysis tools will provide a better view of sabinene biosynthesis and a greater potential of microbial production. |
| WOS关键词 | CELL-FREE SYSTEMS ; ISOPENTENYL DIPHOSPHATE ; ISOPRENOID BIOSYNTHESIS ; ESCHERICHIA-COLI ; BIOTECHNOLOGICAL PRODUCTION ; SACCHAROMYCES-CEREVISIAE ; MONOTERPENE SYNTHASES ; BORNYL DIPHOSPHATE ; ESSENTIAL OILS ; PATHWAY |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| 出版者 | SPRINGER |
| WOS记录号 | WOS:000424053700001 |
| 资助机构 | National Natural Science Foundation of China(31200030) ; Taishan Scholars Climbing Program of Shandong(tspd20150210) |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/10581]  |
| 专题 | 青岛生物能源与过程研究所_材料生物技术研究中心 |
| 通讯作者 | Xian, Mo; Liu, Huizhou |
| 作者单位 | Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Yujin,Zhang, Haibo,Liu, Hui,et al. Biosynthesis and production of sabinene: current state and perspectives[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(4):1535-1544. |
| APA | Cao, Yujin.,Zhang, Haibo.,Liu, Hui.,Liu, Wei.,Zhang, Rubing.,...&Liu, Huizhou.(2018).Biosynthesis and production of sabinene: current state and perspectives.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,102(4),1535-1544. |
| MLA | Cao, Yujin,et al."Biosynthesis and production of sabinene: current state and perspectives".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 102.4(2018):1535-1544. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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