中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data

文献类型:期刊论文

作者Zhou, Qian1,2; Su, Xiaoquan3,4,5; Jing, Gongchao3,4; Chen, Songlin1,2; Ning, Kang6
刊名BMC GENOMICS
出版日期2018-02-14
卷号19
关键词Quality Control Rna-seq Contamination Identification Alignment Statistics Parallel Computing
ISSN号1471-2164
DOI10.1186/s12864-018-4503-6
文献子类Article
英文摘要Background: RNA-Seq has become one of the most widely used applications based on next-generation sequencing technology. However, raw RNA-Seq data may have quality issues, which can significantly distort analytical results and lead to erroneous conclusions. Therefore, the raw data must be subjected to vigorous quality control (QC) procedures before downstream analysis. Currently, an accurate and complete QC of RNA-Seq data requires of a suite of different QC tools used consecutively, which is inefficient in terms of usability, running time, file usage, and interpretability of the results.
WOS研究方向Biotechnology & Applied Microbiology ; Genetics & Heredity
语种英语
WOS记录号WOS:000425518400001
出版者BIOMED CENTRAL LTD
资助机构National Natural Science Foundation of China(31401076 ; Central Public-interest Scientific Institution Basal Research Fund, CAFS(2016RC-YJ01) ; Shandong Provincial Natural Science Foundation, China(ZR2017ZB0421) ; 31771463 ; 31671374)
源URL[http://ir.qibebt.ac.cn/handle/337004/10643]  
专题中国科学院青岛生物能源与过程研究所
通讯作者Chen, Songlin; Ning, Kang
作者单位1.Chinese Acad Fishery Sci, Key Lab Sustainable Dev Marine Fisheries, Minist Agr, Yellow Sea Fisheries Res Inst, Qingdao 266071, Shandong, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266071, Shandong, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Shandong Key Lab Energy Genet, Qingdao 266101, Shandong, Peoples R China
4.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Single Cell Ctr, Qingdao 266101, Shandong, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
6.Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Hubei Key Lab Bioinformat & Mol Imaging, Minist Educ,Key Lab Mol Biophys,Dept Bioinformat, Wuhan 430074, Hubei, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Qian,Su, Xiaoquan,Jing, Gongchao,et al. RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data[J]. BMC GENOMICS,2018,19.
APA Zhou, Qian,Su, Xiaoquan,Jing, Gongchao,Chen, Songlin,&Ning, Kang.(2018).RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data.BMC GENOMICS,19.
MLA Zhou, Qian,et al."RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data".BMC GENOMICS 19(2018).

入库方式: OAI收割

来源:青岛生物能源与过程研究所

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