An in vitro synthetic biosystem based on acetate for production of phloroglucinol
文献类型：期刊论文
| 作者 | Zhang, Rubing1,2 ; Liu, Wei1; Cao, Yujin1; Xu, Xin1,2; Xian, Mo1; Liu, Huizhou1
|
| 刊名 | BMC BIOTECHNOLOGY
 |
| 出版日期 | 2017-08-08 |
| 卷号 | 17 |
| 关键词 | In Vitro Acetate Acetyl-coa Synthetase Phloroglucinol High Yield |
| DOI | 10.1186/s12896-017-0376-z |
| 文献子类 | Article |
| 英文摘要 | Background: Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established. However, due to approximate 80% of the glucose being transformed into undesirable by-products and biomass, this biosynthesis process only shows a low yield with the highest value of about 0.20 g/g. The industrial applications are usually hindered by the low current productivity and yield and also by the high costs. Generally, several different aspects limit the development of phloroglucinol biosynthesis. The yield of phloroglucinol is one of the most important parameters for its bioconversion especially from economic and ecological points of view. The in vitro biosynthesis of bio-based chemicals, is a flexible alternative with potentially high-yield to in vivo biosynthetic technology. |
| WOS关键词 | ENGINEERING ESCHERICHIA-COLI ; ACETYL-COA CARBOXYLASE ; ACID ; BIOSYNTHESIS ; COENZYME ; GLYCEROL ; FERMENTATION ; ACCUMULATION ; EXPRESSION ; CHEMICALS |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000408016900001 |
| 资助机构 | National Natural Science Foundation of China(21376255 ; Taishan Scholars Climbing Program of Shandong(tspd20150210) ; 21572242) |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/9553]  |
| 专题 | 青岛生物能源与过程研究所_材料生物技术研究中心 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Rubing,Liu, Wei,Cao, Yujin,et al. An in vitro synthetic biosystem based on acetate for production of phloroglucinol[J]. BMC BIOTECHNOLOGY,2017,17. |
| APA | Zhang, Rubing,Liu, Wei,Cao, Yujin,Xu, Xin,Xian, Mo,&Liu, Huizhou.(2017).An in vitro synthetic biosystem based on acetate for production of phloroglucinol.BMC BIOTECHNOLOGY,17. |
| MLA | Zhang, Rubing,et al."An in vitro synthetic biosystem based on acetate for production of phloroglucinol".BMC BIOTECHNOLOGY 17(2017). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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