Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina
文献类型：期刊论文
| 作者 | Zhang, Huidan1,3,4; Feng, Yingang1,3 ; Cui, Qiu1,2,3; Song, Xiaojin1,3
|
| 刊名 | BMC BIOTECHNOLOGY
 |
| 出版日期 | 2017-08-30 |
| 卷号 | 17 |
| 关键词 | Arachidonic Acid Mortierella Alpina Hemoglobin Dissolved Oxygen Fermentation |
| DOI | 10.1186/s12896-017-0388-8 |
| 文献子类 | Article |
| 英文摘要 | Background: Arachidonic acid (ARA, C20:4, n-6), which belongs to the omega-6 series of polyunsaturated fatty acids and has a variety of biological activities, is commercially produced in Mortierella alpina. Dissolved oxygen or oxygen utilization efficiency is a critical factor for Mortierella alpina growth and arachidonic acid production in large-scale fermentation. Overexpression of the Vitreoscilla hemoglobin gene is thought to significantly increase the oxygen utilization efficiency of the cells. |
| WOS关键词 | OIL-PRODUCING FUNGUS ; OLEAGINOUS FUNGUS ; INTRACELLULAR EXPRESSION ; YARROWIA-LIPOLYTICA ; AURANTIOCHYTRIUM SP ; 1S-4 ; TRANSFORMATION ; STRATEGY ; PH ; BIOSYNTHESIS |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000408770200001 |
| 资助机构 | National Key Research and Development Program(2016YFA0601400) ; National Natural Science Foundation of China(41306132) ; National High Technology Research and Development Program of China(2014AA021701) |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/9569]  |
| 专题 | 青岛生物能源与过程研究所_代谢物组学团队 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Shandong, Peoples R China 3.Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Shandong, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Huidan,Feng, Yingang,Cui, Qiu,et al. Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina[J]. BMC BIOTECHNOLOGY,2017,17. |
| APA | Zhang, Huidan,Feng, Yingang,Cui, Qiu,&Song, Xiaojin.(2017).Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina.BMC BIOTECHNOLOGY,17. |
| MLA | Zhang, Huidan,et al."Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina".BMC BIOTECHNOLOGY 17(2017). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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