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An early modern human from Romania with a recent Neanderthal ancestor

文献类型:期刊论文

作者Fu, Qiaomei1,2,3; Hajdinjak, Mateja3; Moldovan, Oana Teodora4; Constantin, Silviu5; Mallick, Swapan2,6,7; Skoglund, Pontus2; Patterson, Nick6; Rohland, Nadin2; Lazaridis, Iosif2; Nickel, Birgit3
刊名NATURE
出版日期2015-08-13
卷号524期号:7564页码:216-+
文献子类Article
英文摘要Neanderthals are thought to have disappeared in Europe approximately 39,000-41,000 years ago but they have contributed 1-3% of the DNA of present-day people in Eurasia(1). Here we analyse DNA from a 37,000-42,000-year-old(2) modern human from Pestera cu Oase, Romania. Although the specimen contains small amounts of human DNA, we use an enrichment strategy to isolate sites that are informative about its relationship to Neanderthals and present-day humans. We find that on the order of 6-9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date. Three chromosomal segments of Neanderthal ancestry are over 50 centimorgans in size, indicating that this individual had a Neanderthal ancestor as recently as four to six generations back. However, the Oase individual does not share more alleles with later Europeans than with East Asians, suggesting that the Oase population did not contribute substantially to later humans in Europe.
WOS关键词GENOME SEQUENCE ; ANCIENT DNA ; EUROPEANS ; CAVE ; ADMIXTURE ; HISTORY ; POPULATIONS ; ORIGINS ; SIBERIA ; SYSTEMS
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000359386900031
源URL[http://124.16.247.212/handle/311034/7483]  
专题古脊椎动物与古人类研究所_图书馆1
作者单位1.Chinese Acad Sci, IVPP, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China
2.Harvard Univ, Dept Genet, Sch Med, Boston, MA 02115 USA
3.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany
4.Emil Racovita Inst Speleol, Cluj Branch, Cluj Napoca 400006, Romania
5.Emil Racovita Inst Speleol, Dept Geospeleol & Paleontol, Bucharest 010986 12, Romania
6.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
7.Max Planck Inst Evolutionary Anthropol, Dept Human Evolut, D-04103 Leipzig, Germany
8.Univ Toronto, Dept Anthropol, Toronto, ON M5S 2S2, Canada
9.Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA USA
推荐引用方式
GB/T 7714
Fu, Qiaomei,Hajdinjak, Mateja,Moldovan, Oana Teodora,et al. An early modern human from Romania with a recent Neanderthal ancestor[J]. NATURE,2015,524(7564):216-+.
APA Fu, Qiaomei.,Hajdinjak, Mateja.,Moldovan, Oana Teodora.,Constantin, Silviu.,Mallick, Swapan.,...&Paeaebo, Svante.(2015).An early modern human from Romania with a recent Neanderthal ancestor.NATURE,524(7564),216-+.
MLA Fu, Qiaomei,et al."An early modern human from Romania with a recent Neanderthal ancestor".NATURE 524.7564(2015):216-+.

入库方式: OAI收割

来源:古脊椎动物与古人类研究所

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