A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles
文献类型：期刊论文
| 作者 | Qu, Hongnan1,2,3,4; Yang, Liangrong2; Yu, Jiemiao2; Dong, Tingting2,3; Rong, Meng2,3; Zhang, Jianfeng2,3,4; Xing, Huifang2 ; Wang, Li2; Pan, Feng2; Liu, Huizhou2
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:57页码:35704-35710 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c7ra04444e |
| 文献子类 | Article |
| 英文摘要 | A novel redox responsive controlled release system based on the host-guest interaction between ferrocene modified mesoporous silica nanoparticles (MSN-Fc) and beta-cyclodextrin modified gold nanoparticles (Au@CD) was developed. FITC was used as the release molecule and it was loaded into the pores of MSN-Fc. With the addition of oxidant (H2O2), oxidized ferrocene leaves the hydrophobic cavity of b-CD, resulting in cargo controlled release. Due to the structural properties of the modified MSN, the continuously slow release behavior showed the prospect to be a sustained drug delivery system. This novel redox responsive system possessed stimuli-responsive controlled release and sustained release properties, and therefore has potential applications in sustained and targeted drug delivery. |
| WOS关键词 | OPERATED MECHANIZED NANOPARTICLES ; DRUG-DELIVERY ; MAGNETIC NANOPARTICLES ; GUEST MOLECULES ; CARGO RELEASE ; IN-VITRO ; PH ; NANOVALVES ; ENZYME ; NANOCARRIERS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000406104300018 |
| 资助机构 | National Natural Science Foundation of China(21676273) ; National Key Natural Science Foundation of China(U1507203) ; National Technology Research and Development Program of China(2015CB251402) ; Youth Innovation Promotion Association, CAS(2016043) |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/22982]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Sinodanish Ctr Educ & Res, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qu, Hongnan,Yang, Liangrong,Yu, Jiemiao,et al. A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles[J]. RSC ADVANCES,2017,7(57):35704-35710. |
| APA | Qu, Hongnan.,Yang, Liangrong.,Yu, Jiemiao.,Dong, Tingting.,Rong, Meng.,...&Liu, Huizhou.(2017).A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles.RSC ADVANCES,7(57),35704-35710. |
| MLA | Qu, Hongnan,et al."A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles".RSC ADVANCES 7.57(2017):35704-35710. |
入库方式： OAI收割
来源：过程工程研究所
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