Tunable near-infrared fluorescent gold nanoclusters: temperature sensor and targeted bioimaging
文献类型：期刊论文
| 作者 | Sun, Yuanqing; Wu, Jiapeng; Wang, Chuanxi; Zhao, Yueqi; Lin, Quan |
| 刊名 | NEW JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2017 |
| 卷号 | 41期号:13页码:5412-5419 |
| ISSN号 | 1144-0546 |
| 英文摘要 | Near-infrared (NIR) fluorescence nanomaterials with low toxicity and long wavelength emission play an important role in bioapplications. Herein, a simple and rapid microwave heating method is designed to synthesize fluorescent gold nanoclusters (AuNCs) by using glutathione (GSH) as a reducing agent and stabilizing agent simultaneously. By adjusting the microwave heating time, the as-prepared GSH-AuNCs can show size-dependent tunable fluorescence from the visible region to the NIR region, and even to 800 nm wavelength. Besides, the as-prepared GSH-AuNCs are water-soluble, low toxicity and highly stable, and exhibit multifunctional surface chemistry based on GSH as the protective surface layer. Another attractive feature of the resultant NIR GSH-AuNCs is temperature-dependent fluorescence and they could be used as a nanoprobe to measure the temperature in the range from 0 to 80 degrees C. Moreover, this process is reversible, which means that the fluorescence intensity of the GSH-AuNCs can be recovered to the initial intensity when the temperature changes reversibly. Finally, the resultant NIR GSH-AuNCs are further conjugated with folic acids (FAs) which helps the AuNCs target HeLa cells. These properties provide FA-conjugated GSH-AuNCs with potential applications as a platform for cancer diagnosis studies in various biological systems. |
| 公开日期 | 2017-12-25 |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/13735]  |
| 专题 | 2017专题 |
| 推荐引用方式 GB/T 7714 | Sun, Yuanqing,Wu, Jiapeng,Wang, Chuanxi,et al. Tunable near-infrared fluorescent gold nanoclusters: temperature sensor and targeted bioimaging[J]. NEW JOURNAL OF CHEMISTRY,2017,41(13):5412-5419. |
| APA | Sun, Yuanqing,Wu, Jiapeng,Wang, Chuanxi,Zhao, Yueqi,&Lin, Quan.(2017).Tunable near-infrared fluorescent gold nanoclusters: temperature sensor and targeted bioimaging.NEW JOURNAL OF CHEMISTRY,41(13),5412-5419. |
| MLA | Sun, Yuanqing,et al."Tunable near-infrared fluorescent gold nanoclusters: temperature sensor and targeted bioimaging".NEW JOURNAL OF CHEMISTRY 41.13(2017):5412-5419. |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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