Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform
文献类型：期刊论文
| 作者 | Wu, Sudong; Sun, Peng; Li, Zhen; Wang, Jingyun; Gao, Hui; Yang, Xi; Liu, Deqiang; Chen, Qixian |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2018 |
| 卷号 | 54期号:80页码:11304-11307 |
| 关键词 | Gene Delivery Transfection Polyplexes Polymers Therapy Systems Safe |
| 英文摘要 | A supramolecular catiomer with a metal-organic framework (MOF) motif was developed to manufacture messenger RNA (mRNA) assemblies. In contrast to the linear catiomer, the dendritic MOF catiomer appeared to markedly improve the colloidal stability of the mRNA assemblies, particularly affording substantial protection to the mRNA payloads from enzymatic degradation, eventually conducing to appreciable mRNA transfection activities at the targeted cells. |
| 学科主题 | Chemistry ; Materials Science |
| 语种 | 英语 |
| 公开日期 | 2018-12-04 |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/17127]  |
| 专题 | 2018专题 |
| 推荐引用方式 GB/T 7714 | Wu, Sudong,Sun, Peng,Li, Zhen,et al. Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform[J]. CHEMICAL COMMUNICATIONS,2018,54(80):11304-11307. |
| APA | Wu, Sudong.,Sun, Peng.,Li, Zhen.,Wang, Jingyun.,Gao, Hui.,...&Chen, Qixian.(2018).Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform.CHEMICAL COMMUNICATIONS,54(80),11304-11307. |
| MLA | Wu, Sudong,et al."Transcellular delivery of messenger RNA payloads by a cationic supramolecular MOF platform".CHEMICAL COMMUNICATIONS 54.80(2018):11304-11307. |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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