Interesting optical variations of the etching of Au Nanobipyramid@Ag Nanorods and its application as a colorful chromogenic substrate for immunoassays
文献类型：期刊论文
| 作者 | Chen, Guonan; Lin, Yi; Xu, Shaohua; Yang, Jiao; Huang, Youju; Chen, Zhitao; Qiu, Bin; Lin, Zhenyu; Guo, Longhua |
| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
 |
| 出版日期 | 2018 |
| 卷号 | 267页码:502-509 |
| 关键词 | Squamous-cell Carcinoma Colorimetric Sensors Gold Nanorods Antigen Immunosensor Nanostructures Nanoparticles Fluorescent Elisa Serum |
| 英文摘要 | Common colorimetric immunoassays only show monochromatic intensity variations, and the absorbance intensity is utilized for the quantitative detection of the analytes. Herein, we demonstrate for the first time that Au Nanobipyramid@Ag Nanorods (Au NBP@Ag) is an ideal multicolor chromogenic substrate for immunoassays which combines the absorbance intensity with the Localized Surface Plasmon Resonance (LSPR) peak shifts are utilized for quantitative detection of the analytes, and vivid color variations are used for semi-quantitative detection. Our investigation reveals that unlike the single metallic nanoparticles such as gold nanorods which show one-way LSPR peak shifts, Au NBP@Ag Nanorods shows an interesting multi-way peak shifts: the LSPR peak would initially blue shift, and then red shift, finally blue shift again during the etching process. As a result, a series of vivid colors can be observed. The results indicate that the correlation linear range for the detection of Squamous cell carcinoma antigen (SCCA) was 2.5-105 ng/mL. Although only the detection of SCCA is demonstrated in this work, this method is easy to expand to detect other biomarkers since our method is based on conventional immunoassay strategy. (C) 2018 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry |
| 语种 | 英语 |
| 公开日期 | 2018-12-04 |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/17260]  |
| 专题 | 2018专题 |
| 推荐引用方式 GB/T 7714 | Chen, Guonan,Lin, Yi,Xu, Shaohua,et al. Interesting optical variations of the etching of Au Nanobipyramid@Ag Nanorods and its application as a colorful chromogenic substrate for immunoassays[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,267:502-509. |
| APA | Chen, Guonan.,Lin, Yi.,Xu, Shaohua.,Yang, Jiao.,Huang, Youju.,...&Guo, Longhua.(2018).Interesting optical variations of the etching of Au Nanobipyramid@Ag Nanorods and its application as a colorful chromogenic substrate for immunoassays.SENSORS AND ACTUATORS B-CHEMICAL,267,502-509. |
| MLA | Chen, Guonan,et al."Interesting optical variations of the etching of Au Nanobipyramid@Ag Nanorods and its application as a colorful chromogenic substrate for immunoassays".SENSORS AND ACTUATORS B-CHEMICAL 267(2018):502-509. |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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