Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina
文献类型：期刊论文
| 作者 | Zhang, Huidan1,4,5; Lu, Dong2; Li, Xin2; Feng, Yingang1,4 ; Cui, Qiu1,3,4; Song, Xiaojin1,4
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| 刊名 | BMC BIOTECHNOLOGY
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| 出版日期 | 2018-05-02 |
| 卷号 | 18 |
| 关键词 | Arachidonic Acid Desaturase Heavy Ion Mutagenesis Mortierella Alpina Octyl Gallate Triclosan |
| ISSN号 | 1472-6750 |
| DOI | 10.1186/s12896-018-0437-y |
| 文献子类 | Article |
| 英文摘要 | Background: Arachidonic acid (ARA), which is omega-6 polyunsaturated fatty acid, has a wide range of biological activities and is an essential component of cellular membranes in some human tissues. Mortierella alpina is the best strain for industrial production of ARA. To increase its yield of arachidonic acid, heavy ion beam irradiation mutagenesis of Mortierella alpina was carried out in combination with triclosan and octyl gallate treatment. |
| WOS关键词 | RICH OIL PRODUCTION ; OCTYL-GALLATE ; FERMENTATION STRATEGY ; STRAIN IMPROVEMENT ; ALKYL-GALLATE ; FUNGUS ; 1S-4 ; 5-FLUOROURACIL ; TRANSFORMATION ; IRRADIATION |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000431276200001 |
| 出版者 | BIOMED CENTRAL LTD |
| 资助机构 | National Key Research and Development Program(2016YFA0601400) ; Key research and development program of Shandong Province(2017YYSP026) ; Qingdao independent innovation major project(16-7-1-11-zdzx-nsh) ; Shandong Provincial Key Laboratory of Energy Genetics |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/11531]  |
| 专题 | 中国科学院青岛生物能源与过程研究所 |
| 通讯作者 | Song, Xiaojin |
| 作者单位 | 1.Chinese Acad Sci, Shandong Prov Key Lab Energy Genet, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Shandong, Peoples R China 4.Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Shandong, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Huidan,Lu, Dong,Li, Xin,et al. Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina[J]. BMC BIOTECHNOLOGY,2018,18. |
| APA | Zhang, Huidan,Lu, Dong,Li, Xin,Feng, Yingang,Cui, Qiu,&Song, Xiaojin.(2018).Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina.BMC BIOTECHNOLOGY,18. |
| MLA | Zhang, Huidan,et al."Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina".BMC BIOTECHNOLOGY 18(2018). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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