Aspergixanthones I-K, New Anti-Vibrio Prenylxanthones from the Marine-Derived Fungus Aspergillus sp ZA-01
文献类型：期刊论文
| 作者 | Zhu, Ao1; Zhang, Xing-Wang2 ; Zhang, Miao1; Li, Wan1; Ma, Zheng-Yue1; Zhu, Hua-Jie1; Cao, Fei1
|
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2018-09-01 |
| 卷号 | 16期号:9页码:8 |
| ISSN号 | 1660-3397 |
| 关键词 | marine-derived fungus Aspergillus sp prenylxanthone anti-Vibrio activity |
| DOI | 10.3390/md16090312 |
| 英文摘要 | Marine-derived fungi are a rich source of structurally diverse metabolites. Fungi produce an array of compounds when grown under different cultivation conditions. In the present work, different media were used to cultivate the fungus Aspergillus sp. ZA-01, which was previously studied for the production of bioactive compounds, and three new prenylxanthone derivatives, aspergixanthones I-K (1-3), and four known analogues (4-7) were obtained. The absolute configuration of 1 was assigned by ECD experiment and the Mo-2(AcO)(4) ICD spectrum of its methanolysis derivative (1a). All the compounds (1-7) were evaluated for their anti-Vibrio activities. Aspergixanthone I (1) showed the strongest anti-Vibrio activity against Vibrio parahemolyticus (MIC = 1.56 M), Vibrio anguillarum (MIC = 1.56 M), and Vibrio alginolyticus (MIC = 3.12 M). |
| WOS关键词 | EMERICELLA SP ; DERIVATIVES |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | MDPI |
| WOS记录号 | WOS:000445636600023 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/11632]  |
| 专题 | 中国科学院青岛生物能源与过程研究所 |
| 通讯作者 | Zhu, Hua-Jie; Cao, Fei |
| 作者单位 | 1.Hebei Univ, Coll Pharmaceut Sci, Educ Minist China, Key Lab Pharmaceut Qual Control Hebei Prov,Key La, Baoding 071002, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Shandong Prov Key Lab Synthet Biol, Qingdao 266101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Ao,Zhang, Xing-Wang,Zhang, Miao,et al. Aspergixanthones I-K, New Anti-Vibrio Prenylxanthones from the Marine-Derived Fungus Aspergillus sp ZA-01[J]. MARINE DRUGS,2018,16(9):8. |
| APA | Zhu, Ao.,Zhang, Xing-Wang.,Zhang, Miao.,Li, Wan.,Ma, Zheng-Yue.,...&Cao, Fei.(2018).Aspergixanthones I-K, New Anti-Vibrio Prenylxanthones from the Marine-Derived Fungus Aspergillus sp ZA-01.MARINE DRUGS,16(9),8. |
| MLA | Zhu, Ao,et al."Aspergixanthones I-K, New Anti-Vibrio Prenylxanthones from the Marine-Derived Fungus Aspergillus sp ZA-01".MARINE DRUGS 16.9(2018):8. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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