Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli
文献类型：期刊论文
| 作者 | Li, Meijie1,2; Nian, Rui1; Xian, Mo1 ; Zhang, Haibo1
|
| 刊名 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
 |
| 出版日期 | 2018-09-01 |
| 卷号 | 102期号:18页码:7725-7738 |
| 关键词 | Isoprene Isopentenol MVA MEP Metabolic engineering |
| ISSN号 | 0175-7598 |
| DOI | 10.1007/s00253-018-9200-5 |
| 英文摘要 | The biotechnological production of isoprene and isopentenol has recently been studied. Isoprene, which is currently made mainly from petroleum, is an important platform chemical for synthesizing pesticides, medicines, oil additives, fragrances, and more and is especially important in the rubber production industry. Isopentenols, which have better combustion properties than well-known biofuels (ethanol), have recently received more attention. Supplies of petroleum, the conventional source of isoprene and isopentenols, are unsustainable, and chemical synthesis processes could cause serious environmental problems. As an alternative, the biosynthesis of isoprene and isopentenols in cell factories is more sustainable and environmentally friendly. With a number of advantages over other microorganisms, Escherichia coli is considered to be a powerful workhorse organism for producing these compounds. This review will highlight the recent advances in metabolic engineering for isoprene and isopentenol production, especially using E. coli cell factories. |
| WOS关键词 | METHYLERYTHRITOL PHOSPHATE-PATHWAY ; HMG-COA REDUCTASE ; MEVALONATE PATHWAY ; BACILLUS-SUBTILIS ; CAROTENOID BIOSYNTHESIS ; DIPHOSPHATE SYNTHASE ; 4FE-4S PROTEIN ; EXPRESSION ; EMISSION ; PLANTS |
| 资助项目 | National Natural Science Foundation of China (NSF)[31400084] ; Hainan's Key Project of Research and Development Plan[ZDYF2017155] ; Taishan Scholars Climbing Program of Shandong[TSPD20150210] ; Youth Innovation Promotion Association (CAS)[2017252] |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000442570500007 |
| 出版者 | SPRINGER |
| 资助机构 | National Natural Science Foundation of China (NSF) ; Hainan's Key Project of Research and Development Plan ; Taishan Scholars Climbing Program of Shandong ; Youth Innovation Promotion Association (CAS) |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/11890]  |
| 专题 | 中国科学院青岛生物能源与过程研究所 |
| 通讯作者 | Xian, Mo; Zhang, Haibo |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, 135 Songling Rd, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Meijie,Nian, Rui,Xian, Mo,et al. Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2018,102(18):7725-7738. |
| APA | Li, Meijie,Nian, Rui,Xian, Mo,&Zhang, Haibo.(2018).Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,102(18),7725-7738. |
| MLA | Li, Meijie,et al."Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 102.18(2018):7725-7738. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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