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Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure D(-)-tartaric acid

文献类型：期刊论文

作者Dong, Sheng1,2,3; Liu, Xi4,5; Cui, Gu-Zhen1,2,3,6; Cui, Qiu1,2,3; Wang, Xinquan4; Feng, Yingang1,2,3
刊名CHEMICAL COMMUNICATIONS
出版日期2018-08-07
卷号54期号:61页码:8482-8485
ISSN号1359-7345
DOI10.1039/c8cc04398a
英文摘要Crystal structure determination and mutagenesis analysis of a cis-epoxysuccinate hydrolase which produces enantiomerically pure D(-)-tartaric acids revealed a zinc ion and essential residues in the stereoselective mechanism for the catalytic reaction of the small mirror symmetric substrate.
WOS关键词MICROBIAL EPOXIDE HYDROLASES ; ENZYME ; FOLD ; EXPRESSION ; STABILITY ; CLONING
资助项目National Natural Science Foundation of China[31670735] ; National Natural Science Foundation of China[31661143023] ; National Natural Science Foundation of China[31470210] ; National Natural Science Foundation of China[31700694] ; National Natural Science Foundation of China[31470751] ; National Natural Science Foundation of China[U1405228]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000442124900011
出版者ROYAL SOC CHEMISTRY
资助机构National Natural Science Foundation of China
源URL[http://ir.qibebt.ac.cn/handle/337004/12139]  
专题中国科学院青岛生物能源与过程研究所
通讯作者Cui, Qiu; Wang, Xinquan; Feng, Yingang
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, Songling Rd 189, Qingdao 266101, Shandong, Peoples R China
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Songling Rd 189, Qingdao 266101, Shandong, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Shandong, Peoples R China
4.Tsinghua Univ, Sch Life Sci, Ctr Struct Biol, Minist Educ,Key Lab Prot Sci, Beijing 100084, Peoples R China
5.Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94158 USA
6.Guizhou Med Univ, Sch Basic Med Sci, Guiyang 550025, Guizhou, Peoples R China
推荐引用方式
GB/T 7714		 Dong, Sheng,Liu, Xi,Cui, Gu-Zhen,et al. Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure D(-)-tartaric acid[J]. CHEMICAL COMMUNICATIONS,2018,54(61):8482-8485.
APA Dong, Sheng,Liu, Xi,Cui, Gu-Zhen,Cui, Qiu,Wang, Xinquan,&Feng, Yingang.(2018).Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure D(-)-tartaric acid.CHEMICAL COMMUNICATIONS,54(61),8482-8485.
MLA Dong, Sheng,et al."Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure D(-)-tartaric acid".CHEMICAL COMMUNICATIONS 54.61(2018):8482-8485.

入库方式： OAI收割

来源：青岛生物能源与过程研究所

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