Degradable rhenium trioxide nanocubes with high localized surface plasmon resonance absorbance like gold for photothermal theranostics
文献类型：期刊论文
| 作者 | Zhang, Wenlong; Deng, Guoying1; Li, Bo2; Zhao, Xinxin3; Ji, Tao; Song, Guosheng4; Xiao, Zhiyin5; Cao, Qing; Xiao, Jingbo6,7; Huang, Xiaojuan |
| 刊名 | BIOMATERIALS
 |
| 出版日期 | 2018 |
| 卷号 | 159页码:68 |
| 关键词 | Degradable rhenium trioxide Nanocubes Photothermal theranostic agents Inorganic nanomaterials Space-confined on-substrate route |
| ISSN号 | 0142-9612 |
| DOI | 10.1016/j.biomaterials.2017.12.021 |
| 英文摘要 | The applications of inorganic theranostic agents in clinical trials are generally limited to their innate non biodegradability and potential long-term biotoxicity. To address this problem, herein via a straightforward and tailored space-confined on-substrate route, we obtained rhenium trioxide (ReO3) nanocubes (NCs) that display a good biocompatibility and biosafety. Importantly, their aqueous dispersion has high localized surface plasmon resonance (LSPR) absorbance in near-infrared (NIR) region different from previous report, which possibly associates with the charge transfer and structural distortion in hydrogen rhenium bronze (HxReO3), as well as ReO3's cubic shape. Such a high LSPR absorbance in the NIR region endows them with photoacoustic (PA)/infrared (IR) thermal imaging, and high photothermal conversion efficiency (-57.0%) for efficient ablation of cancer cells. Also, ReO3 NCs show X-ray computed tomography (CT) imaging derived from the high-Z element Re. More attractively, those ReO3 NCs, with pH-dependent oxidized degradation behaviors, are revealed to be relatively stable in hypoxic and weakly acidic microenvironment of tumor for imaging and treatment whilst degradable in normal physiological environments of organs to enable effective clearance. In spite of their degradability, ReO3 NCs still possess tumor targeting capabilities. We thus develop a simple but powerful, safe and biodegradable inorganic theranostic platform to achieve PA/CT/IR imaging-guided cancer photothermal therapy (MT) for improved therapeutic efficacy and decreased toxic side effects. (C) 2018 Elsevier Ltd. All rights reserved. |
| 学科主题 | Engineering, Biomedical ; Materials Science, bioMaterials |
| WOS记录号 | WOS:000425070900007 |
| 出版者 | ELSEVIER SCI LTD |
| 资助机构 | This work was financially supported by the National Natural Science Foundation of China (grant no. 51472049, 51741203, 51672044 and 51702348), the Shanghai Pujiang Program (grant no. 16PJ1400200), the the Shanghai Sailing Program (17YF1421400), the Program for Innovative Research Team in University of Ministry of Education of China (IRT_16R13), the DHU Distinguished Young Professor Program and the Fundamental Research Funds for the Central Universities. ; This work was financially supported by the National Natural Science Foundation of China (grant no. 51472049, 51741203, 51672044 and 51702348), the Shanghai Pujiang Program (grant no. 16PJ1400200), the the Shanghai Sailing Program (17YF1421400), the Program for Innovative Research Team in University of Ministry of Education of China (IRT_16R13), the DHU Distinguished Young Professor Program and the Fundamental Research Funds for the Central Universities. |
| 源URL | [http://ir.sic.ac.cn/handle/331005/24440]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Donghua Univ, Coll Mat Sci & Engn, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China 2.Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Trauma Ctr, Sch Med, Shanghai 201620, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 4.Shanghai Univ Engn Sci, Sch Math Phys & Stat, Shanghai 201620, Peoples R China 5.Stanford Univ, Sch Med, Dept Radiol, Mol Imaging Program Stanford, 1201 Welch Rd, Stanford, CA 94305 USA 6.Jiaxing Univ, Coll Biol Chem Sci & Engn, Jiaxing 314001, Peoples R China 7.Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Shanghai Key Lab Pancreat Dis, Sch Med, Shanghai 201620, Peoples R China 8.Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Dept Gastroenterol, Sch Med, Shanghai 201620, Peoples R China 9.Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Vasc Surg, Sch Med, Shanghai 200011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Wenlong,Deng, Guoying,Li, Bo,et al. Degradable rhenium trioxide nanocubes with high localized surface plasmon resonance absorbance like gold for photothermal theranostics[J]. BIOMATERIALS,2018,159:68, 81. |
| APA | Zhang, Wenlong.,Deng, Guoying.,Li, Bo.,Zhao, Xinxin.,Ji, Tao.,...&Hu, Junqing.(2018).Degradable rhenium trioxide nanocubes with high localized surface plasmon resonance absorbance like gold for photothermal theranostics.BIOMATERIALS,159,68. |
| MLA | Zhang, Wenlong,et al."Degradable rhenium trioxide nanocubes with high localized surface plasmon resonance absorbance like gold for photothermal theranostics".BIOMATERIALS 159(2018):68. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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