In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement
文献类型：期刊论文
| 作者 | Xu, Chen1; Wen, Yang2,3,4; Zhou, Yanling; Zhu, Yaqin2,3,4; Dou, Yuandong5; Huan, Zhiguang; Chang, Jiang |
| 刊名 | INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
 |
| 出版日期 | 2018 |
| 卷号 | 15期号:2页码:460 |
| 关键词 | calcium chloride dental application premixed pastes tricalcium silicate |
| ISSN号 | 1546-542X |
| DOI | 10.1111/ijac.12813 |
| 英文摘要 | The clinical use of cements in root canal treatment needs the dentist to mix the powders and liquid phase thoroughly. The operation not only increases the surgery time but also compromises the performance of cement in case of inhomogeneous or insufficient mixing. To overcome those drawbacks, a premixed tricalcium silicate cement (C3S) was prepared by mixing tricalcium silicate/calcium chloride (C3S/CaCl2) composites with polyethylene glycol (PEG). It was found that the setting time could be modulated by changing the content of CaCl2 in the solid phase and the liquid to solid ratio (L/P). In addition, the premixed pastes retained the bioactivity of C3S, such as the ability to induce apatite formation in simulated oral fluid and to promote the proliferation and the alkaline phosphate (ALP) activity of human dental pulp stem cells (hDPSCs). Meanwhile, the injected pastes showed good antibacterial ability against Staphylococcus aureus. It is thus expected that the premixed C3S/CaCl2 pastes hold great promise as a new type of materials for dental application. |
| 学科主题 | Materials Science, Ceramics |
| WOS记录号 | WOS:000424816400021 |
| 出版者 | WILEY |
| 资助机构 | National Natural Science Foundation of China, Grant/Award Number: 81190132, 81401529 ; National Natural Science Foundation of China, Grant/Award Number: 81190132, 81401529 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/24448]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Shanghai Jiao Tong Univ, Peoples Hosp 9, Dept Gen Dent, Sch Med, Shanghai, Peoples R China 4.Natl Clin Res Ctr Stomatol, Shanghai Key Lab Stomatol, Shanghai, Peoples R China 5.Natl Clin Res Ctr Stomatol, Shanghai Res Inst Stomatol, Shanghai, Peoples R China 6.Yantai Zhenghai Biotech Co Ltd, Yantai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Chen,Wen, Yang,Zhou, Yanling,et al. In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement[J]. INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,2018,15(2):460, 471. |
| APA | Xu, Chen.,Wen, Yang.,Zhou, Yanling.,Zhu, Yaqin.,Dou, Yuandong.,...&Chang, Jiang.(2018).In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement.INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,15(2),460. |
| MLA | Xu, Chen,et al."In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement".INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY 15.2(2018):460. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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