中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties

文献类型:期刊论文

作者Fu, Shengyang1; Liu, Wei2; Liu, Shiwei1; Zhao, Shichang2; Zhu, Yufang1,3,4
刊名Science and Technology of Advanced Materials
出版日期2018
卷号19期号:1页码:495-506
ISSN号14686996
DOI10.1080/14686996.2018.1471653
英文摘要Silicate bioceramic scaffolds are of great interest in bone tissue engineering, but the fabrication of silicate bioceramic scaffolds with complex geometries is still challenging. In this study, three-dimensional (3D) porous β-Ca2SiO4 scaffolds have been successfully fabricated from preceramic resin loaded with CaCO3 active filler by 3D printing. The fabricated β-Ca2SiO4 scaffolds had uniform interconnected macropores (ca. 400 μm), high porosity (>78%), enhanced mechanical strength (ca. 5.2 MPa), and excellent apatite mineralization ability. Importantly, the results showed that the increase of sintering temperature significantly enhanced the compressive strength and the scaffolds sintered at higher sintering temperature stimulated the adhesion, proliferation, alkaline phosphatase activity, and osteogenic-related gene expression of rat bone mesenchymal stem cells. Therefore, the 3D printed β-Ca2SiO4 scaffolds derived from preceramic resin and CaCO3 active fillers would be promising candidates for bone tissue engineering. © 2018, © 2018 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis Group.
出版者Taylor and Francis Ltd.
源URL[http://ir.sic.ac.cn/handle/331005/25167]  
专题中国科学院上海硅酸盐研究所
作者单位1.School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China;
2.Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, China;
3.Shanghai Innovation Institute for Materials, Shanghai, China;
4.Hubei Key Laboratory of Processing and Application of Catalytic Materials, College of Chemical Engineering, Huanggang Normal University, Huanggang City; Hubei Province, China
推荐引用方式
GB/T 7714
Fu, Shengyang,Liu, Wei,Liu, Shiwei,et al. 3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties[J]. Science and Technology of Advanced Materials,2018,19(1):495-506.
APA Fu, Shengyang,Liu, Wei,Liu, Shiwei,Zhao, Shichang,&Zhu, Yufang.(2018).3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties.Science and Technology of Advanced Materials,19(1),495-506.
MLA Fu, Shengyang,et al."3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties".Science and Technology of Advanced Materials 19.1(2018):495-506.

入库方式: OAI收割

来源:上海硅酸盐研究所

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