3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties
文献类型:期刊论文
作者 | Fu, Shengyang1; Liu, Wei2; Liu, Shiwei1; Zhao, Shichang2; Zhu, Yufang1,3,4 |
刊名 | Science and Technology of Advanced Materials
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出版日期 | 2018 |
卷号 | 19期号:1页码:495-506 |
ISSN号 | 14686996 |
DOI | 10.1080/14686996.2018.1471653 |
英文摘要 | Silicate bioceramic scaffolds are of great interest in bone tissue engineering, but the fabrication of silicate bioceramic scaffolds with complex geometries is still challenging. In this study, three-dimensional (3D) porous β-Ca2SiO4 scaffolds have been successfully fabricated from preceramic resin loaded with CaCO3 active filler by 3D printing. The fabricated β-Ca2SiO4 scaffolds had uniform interconnected macropores (ca. 400 μm), high porosity (>78%), enhanced mechanical strength (ca. 5.2 MPa), and excellent apatite mineralization ability. Importantly, the results showed that the increase of sintering temperature significantly enhanced the compressive strength and the scaffolds sintered at higher sintering temperature stimulated the adhesion, proliferation, alkaline phosphatase activity, and osteogenic-related gene expression of rat bone mesenchymal stem cells. Therefore, the 3D printed β-Ca2SiO4 scaffolds derived from preceramic resin and CaCO3 active fillers would be promising candidates for bone tissue engineering. © 2018, © 2018 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis Group. |
出版者 | Taylor and Francis Ltd. |
源URL | [http://ir.sic.ac.cn/handle/331005/25167] ![]() |
专题 | 中国科学院上海硅酸盐研究所 |
作者单位 | 1.School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China; 2.Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, China; 3.Shanghai Innovation Institute for Materials, Shanghai, China; 4.Hubei Key Laboratory of Processing and Application of Catalytic Materials, College of Chemical Engineering, Huanggang Normal University, Huanggang City; Hubei Province, China |
推荐引用方式 GB/T 7714 | Fu, Shengyang,Liu, Wei,Liu, Shiwei,et al. 3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties[J]. Science and Technology of Advanced Materials,2018,19(1):495-506. |
APA | Fu, Shengyang,Liu, Wei,Liu, Shiwei,Zhao, Shichang,&Zhu, Yufang.(2018).3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties.Science and Technology of Advanced Materials,19(1),495-506. |
MLA | Fu, Shengyang,et al."3D printed porous β-Ca2SiO4 scaffolds derived from preceramic resin and their physicochemical and biological properties".Science and Technology of Advanced Materials 19.1(2018):495-506. |
入库方式: OAI收割
来源:上海硅酸盐研究所
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