Strength, toughness, and reliability of a porous glass/biopolymer composite scaffold
文献类型：期刊论文
| 作者 | Fu, Qiang1; Jia, Weitao2; Lau, Grace Y.1; Tomsia, Antoni P.1 |
| 刊名 | Journal of Biomedical Materials Research - Part B Applied Biomaterials
 |
| 出版日期 | 2018 |
| 卷号 | 106期号:3页码:1209-1217 |
| ISSN号 | 15524973 |
| DOI | 10.1002/jbm.b.33924 |
| 英文摘要 | Development of bioactive glass and ceramic scaffolds intended for the reconstruction of large segmental bone defects remains a challenge for materials science due to the complexities involved in clinical implantation, bone–implant reaction, implant degradation and the multiple loading modes the implants subjected to. A comprehensive evaluation of the mechanical properties of inorganic scaffolds and exploration of new ways to toughen brittle constructs are critical prior to their successful application in loaded sites. A simple and widely adopted approach involves the coating of an inorganic scaffold with a polymeric material. In this work, a systematic evaluation of the influence of a biopolymer, polycaprolactone (PCL), coating on the mechanical performance of bioactive glass scaffolds was carried out. Results from this work indicate that a biopolymer PCL coating was more effective in increasing the compressive strength and reliability of the glass scaffold under compression, but less effective in improving its flexural strength or fracture toughness. This is the first report that reveals the limited successfulness of a polymer coating in improving the toughness of strong scaffolds, suggesting that new and novel ways of toughening inorganic scaffolds should be future research directions for scaffolds applied in loaded sites. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1209–1217, 2018. © 2017 Wiley Periodicals, Inc. |
| 出版者 | John Wiley and Sons Inc., P.O.Box 18667, Newark, NJ 07191-8667, United States |
| 源URL | [http://ir.sic.ac.cn/handle/331005/25340]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley; CA; 94720, United States; 2.Department of Orthopedic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai; 200233, China |
| 推荐引用方式 GB/T 7714 | Fu, Qiang,Jia, Weitao,Lau, Grace Y.,et al. Strength, toughness, and reliability of a porous glass/biopolymer composite scaffold[J]. Journal of Biomedical Materials Research - Part B Applied Biomaterials,2018,106(3):1209-1217. |
| APA | Fu, Qiang,Jia, Weitao,Lau, Grace Y.,&Tomsia, Antoni P..(2018).Strength, toughness, and reliability of a porous glass/biopolymer composite scaffold.Journal of Biomedical Materials Research - Part B Applied Biomaterials,106(3),1209-1217. |
| MLA | Fu, Qiang,et al."Strength, toughness, and reliability of a porous glass/biopolymer composite scaffold".Journal of Biomedical Materials Research - Part B Applied Biomaterials 106.3(2018):1209-1217. |
入库方式： OAI收割
来源：上海硅酸盐研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。