Two-dimensional black phosphorus nanosheets for theranostic nanomedicine
文献类型：期刊论文
| 作者 | Qian, Xiaoqin1; Gu, Zi2; Chen, Yu3 |
| 刊名 | Materials Horizons
 |
| 出版日期 | 2017 |
| 卷号 | 4期号:5页码:800-816 |
| ISSN号 | 20516347 |
| DOI | 10.1039/c7mh00305f |
| 英文摘要 | The fast progress of theranostic nanomedicine has catalyzed the generation of diverse inorganic nanosystems with intrinsic multifunctionalities for versatile biomedical applications. However, these inorganic biomaterials suffer from the critical issue of low biodegradation rates and subsequently long-term accumulation-induced biosafety risk. Furthermore, the components of some inorganic nanosystems are not the necessary elements/components of the body, unavoidably causing immune response and inducing the toxic potential. The emergence of ultrathin two-dimensional black phosphorus (B.P.) nanosheets as a robust platform promises the clinical translation and biomedical applications of inorganic nanosystems based on their intriguing nature of easy biodegradation and single phosphorus composition, as necessarily required in vivo. This review summarizes and discusses the very recent developments and paradigms of ultrathin B.P. nanosheets in versatile biomedical applications, ranging from design/fabrication strategies, theranostic nanomedicine (PDT/PTT/chemotherapy, synergistic therapy and fluorescence/photoacoustic-based bio-imaging) to biosensing applications. The unique biological behavior and toxicity issue of these B.P. nanosheets are also discussed to guarantee their safe clinical translation. It is highly expected that the elaborately designed/engineered B.P. nanosheets will emerge as one of the most representative biodegradable inorganic nanosystems for versatile and immense biomedical applications to benefit the health of human beings. © 2017 The Royal Society of Chemistry. |
| 源URL | [http://ir.sic.ac.cn/handle/331005/25425]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Department of Ultrasound, Affiliated People's Hospital, Jiangsu University, Zhenjiang, Jiangsu; 212002, China; 2.School of Chemical Engineering, University of New South Wales, Sydney; NSW; 2052, Australia; 3.State Laboratory of High Performance Ceramic and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China |
| 推荐引用方式 GB/T 7714 | Qian, Xiaoqin,Gu, Zi,Chen, Yu. Two-dimensional black phosphorus nanosheets for theranostic nanomedicine[J]. Materials Horizons,2017,4(5):800-816. |
| APA | Qian, Xiaoqin,Gu, Zi,&Chen, Yu.(2017).Two-dimensional black phosphorus nanosheets for theranostic nanomedicine.Materials Horizons,4(5),800-816. |
| MLA | Qian, Xiaoqin,et al."Two-dimensional black phosphorus nanosheets for theranostic nanomedicine".Materials Horizons 4.5(2017):800-816. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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