中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement

文献类型:期刊论文

作者Xu, Chen1,2; Wen, Yang3,4,5; Zhou, Yanling1; Zhu, Yaqin3,4,5; Dou, Yuandong6; Huan, Zhiguang1; Chang, Jiang1
刊名INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
出版日期2018-03-01
卷号15期号:2页码:460-471
关键词Calcium Chloride Dental Application Premixed Pastes Tricalcium Silicate
DOI10.1111/ijac.12813
文献子类Article
英文摘要The clinical use of cements in root canal treatment needs the dentist to mix the powders and liquid phase thoroughly. The operation not only increases the surgery time but also compromises the performance of cement in case of inhomogeneous or insufficient mixing. To overcome those drawbacks, a premixed tricalcium silicate cement (C3S) was prepared by mixing tricalcium silicate/calcium chloride (C3S/CaCl2) composites with polyethylene glycol (PEG). It was found that the setting time could be modulated by changing the content of CaCl2 in the solid phase and the liquid to solid ratio (L/P). In addition, the premixed pastes retained the bioactivity of C3S, such as the ability to induce apatite formation in simulated oral fluid and to promote the proliferation and the alkaline phosphate (ALP) activity of human dental pulp stem cells (hDPSCs). Meanwhile, the injected pastes showed good antibacterial ability against Staphylococcus aureus. It is thus expected that the premixed C3S/CaCl2 pastes hold great promise as a new type of materials for dental application.
WOS关键词MINERAL TRIOXIDE AGGREGATE ; END FILLING MATERIALS ; ROOT-CANAL SEALERS ; TRICALCIUM SILICATE ; PHYSICAL-PROPERTIES ; ODONTOGENIC DIFFERENTIATION ; ANTIMICROBIAL ACTIVITY ; CALCIUM HYDROXIDE ; SEALING ABILITY ; DENTIN
WOS研究方向Materials Science
语种英语
WOS记录号WOS:000424816400021
资助机构National Natural Science Foundation of China(81190132 ; National Natural Science Foundation of China(81190132 ; 81401529) ; 81401529) ; National Natural Science Foundation of China(81190132 ; National Natural Science Foundation of China(81190132 ; 81401529) ; 81401529)
源URL[http://ir.sic.ac.cn/handle/331005/24401]  
专题上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
作者单位1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
3.Shanghai Jiao Tong Univ, Peoples Hosp 9, Dept Gen Dent, Sch Med, Shanghai, Peoples R China
4.Natl Clin Res Ctr Stomatol, Shanghai Key Lab Stomatol, Shanghai, Peoples R China
5.Natl Clin Res Ctr Stomatol, Shanghai Res Inst Stomatol, Shanghai, Peoples R China
6.Yantai Zhenghai Biotech Co Ltd, Yantai, Peoples R China
推荐引用方式
GB/T 7714
Xu, Chen,Wen, Yang,Zhou, Yanling,et al. In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement[J]. INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,2018,15(2):460-471.
APA Xu, Chen.,Wen, Yang.,Zhou, Yanling.,Zhu, Yaqin.,Dou, Yuandong.,...&Chang, Jiang.(2018).In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement.INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,15(2),460-471.
MLA Xu, Chen,et al."In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement".INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY 15.2(2018):460-471.

入库方式: OAI收割

来源:上海硅酸盐研究所

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