Advances in the study of the mechanochemical coupling of kinesin
文献类型：期刊论文
| 作者 | Li, M ; Ou-Yang, ZC; Shu, YG
|
| 刊名 | INTERNATIONAL JOURNAL OF MODERN PHYSICS B
 |
| 出版日期 | 2018 |
| 卷号 | 32期号:18页码:1840001 |
| 关键词 | SQUID GIANT-AXON BOVINE BRAIN KINESIN HAND-OVER-HAND CRYSTAL-STRUCTURE MOTOR DOMAIN NECK LINKER 8-NM STEP MOLECULAR MOTORS OPTICAL-TRAP FORCE |
| ISSN号 | 0217-9792 |
| DOI | 10.1142/S0217979218400015 |
| 英文摘要 | Kinesin is a two-headed linear motor for intracellular transport. It can walk a long distance in a hand-over-hand manner along the track before detaching (i.e., high processivity), and it consumes one ATP molecule for each step (i.e., tight mechanochemical coupling). The mechanisms of the coordination of its two heads and the mechanochemical coupling are the central issues of numerous researches. A few advances have been made in recent decades, thanks to the development of single-molecule technologies and molecular dynamics simulations. In this paper, we review some progress of the studies on the kinematics, energetics, coordination mechanism, mechanochemical mechanism of kinesin. We also present a personal perspective on the future studies of kinesin. |
| 学科主题 | Physics |
| 语种 | 英语 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/22856]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 作者单位 | 1.Univ Chinese Acad Sci, Sch Phys Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Theoret Phys, CAS Key Lab Theoret Phys, Beijing 100190, Peoples R China 3.[Ou-Yang, Zhong-Can 4.[Li, Ming |
| 推荐引用方式 GB/T 7714 | Li, M,Ou-Yang, ZC,Shu, YG. Advances in the study of the mechanochemical coupling of kinesin[J]. INTERNATIONAL JOURNAL OF MODERN PHYSICS B,2018,32(18):1840001. |
| APA | Li, M,Ou-Yang, ZC,&Shu, YG.(2018).Advances in the study of the mechanochemical coupling of kinesin.INTERNATIONAL JOURNAL OF MODERN PHYSICS B,32(18),1840001. |
| MLA | Li, M,et al."Advances in the study of the mechanochemical coupling of kinesin".INTERNATIONAL JOURNAL OF MODERN PHYSICS B 32.18(2018):1840001. |
入库方式： OAI收割
来源：理论物理研究所
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