New prenylated coumarins from the stems of Toddalia asiatica
文献类型：期刊论文
| 作者 | Li, Wei; Zhang, Jun-Sheng; Huang, Jia-Luo; Jiang, Min-Hong; Xu, You-Kai ; Ahmed, Abrar; Yin, Sheng; Tang, Gui-Hua
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:49页码:31061-31068 |
| 英文摘要 | Eight new prenylated coumarins (1a/1b, 2a/2b, and 3-6) including two pairs of enantiomers (1a/1b and 2a/2b), a new phenolic acid derivative, methyl (E)-3,4-bis(4-hydroxyphenyl)-4-oxobut-2-enoate (7), and 33 known compounds (8-40) were isolated from the stems of Toddalia asiatica. Their structures were established from spectroscopic data and by chemical methods. The absolute configurations of two pairs of enantiomers (1a/1b and 2a/2b) were determined by X-ray diffraction analysis together with ECD and specific optical rotation calculations. The inhibitory effects of selected compounds against phosphodiesterase-4 (PDE4) were evaluated, and compounds 12, 19, 21-23, 26, 34, and 35 exhibited PDE4 inhibition activities with IC50 values less than 10 mu M. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 公开日期 | 2018-02-09 |
| 源URL | [http://ir.xtbg.org.cn/handle/353005/10783]  |
| 专题 | 西双版纳热带植物园_民族植物学研究组 |
| 推荐引用方式 GB/T 7714 | Li, Wei,Zhang, Jun-Sheng,Huang, Jia-Luo,et al. New prenylated coumarins from the stems of Toddalia asiatica[J]. RSC ADVANCES,2017,7(49):31061-31068. |
| APA | Li, Wei.,Zhang, Jun-Sheng.,Huang, Jia-Luo.,Jiang, Min-Hong.,Xu, You-Kai.,...&Tang, Gui-Hua.(2017).New prenylated coumarins from the stems of Toddalia asiatica.RSC ADVANCES,7(49),31061-31068. |
| MLA | Li, Wei,et al."New prenylated coumarins from the stems of Toddalia asiatica".RSC ADVANCES 7.49(2017):31061-31068. |
入库方式： OAI收割
来源：西双版纳热带植物园
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