Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate
文献类型:期刊论文
作者 | Wang, Ying1,2; Shen, Yue3![]() |
刊名 | JOURNAL OF PHYSICAL CHEMISTRY B
![]() |
出版日期 | 2018-01-18 |
卷号 | 122期号:2页码:612-617 |
文献子类 | Article |
英文摘要 | Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures. |
WOS关键词 | ATOMIC-FORCE MICROSCOPY ; GRAPHITE OXIDE ; MECHANICAL-PROPERTIES ; BIAXIAL STRAIN ; NANOSHEETS ; PATTERNS |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000423140600026 |
源URL | [http://ir.isl.ac.cn/handle/363002/6414] ![]() |
专题 | 青海盐湖研究所_青海盐湖研究所知识仓储 青海盐湖研究所_盐湖资源与化学实验室 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Key Lab Interfacial Phys & Technol, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Appl Phys, Lab Phys Biol, Shanghai 201800, Peoples R China 3.Chinese Acad Sci, Qinghai Inst Salt Lakes, Key Lab Salt Lake Resources Chem Qinghai Prov, Xining 810008, Qinghai, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Ying,Shen, Yue,Li, Bin,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617. |
APA | Wang, Ying.,Shen, Yue.,Li, Bin.,Wang, Shuo.,Zhang, Jinjin.,...&Hu, Jun.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617. |
MLA | Wang, Ying,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617. |
入库方式: OAI收割
来源:青海盐湖研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。