Enhanced Bioactivity and Bacteriostasis of Surface Fluorinated Polyetheretherketone
文献类型：期刊论文
| 作者 | Chen, Meiling1; Ouyang, Liping2,3; Lu, Tao2; Wang, Heying2; Meng, Fanhao2; Yang, Yan1; Ning, Congqin2; Ma, Jingzhi1; Liu, Xuanyong2 |
| 刊名 | ACS Applied Materials and Interfaces
 |
| 出版日期 | 2017 |
| 卷号 | 9期号:20页码:16824-16833 |
| ISSN号 | 19448244 |
| DOI | 10.1021/acsami.7b02521 |
| 英文摘要 | Although polyetheretherketone (PEEK) has been considered as a potential orthopedic and dental application material due to its similar elastic modulus as bones, inferior osseointegration and bacteriostasis of PEEK hampers its clinical application. In this work, fluorinated PEEK was constructed via plasma immersion ion implantation (PIII) followed by hydrofluoric acid treatment to ameliorate the osseointegration and antibacterial properties of PEEK. The surface microstructure, composition, and hydrophilicity of all samples were investigated. Rat bone mesenchymal stem cells (rBMSCs) were cultured on their surfaces to estimate bioactivity. The fluorinated PEEK can enhance the cell adhesion, cell spreading, proliferation, and alkaline phosphatase (ALP) activity compared to pristine PEEK. Furthermore, the fluorinated PEEK surface exhibits good bacteriostatic effect against Porphyromonas gingivalis, which is one of the major periodontal pathogens. In summary, we provide an effective route to introduce fluorine and the results reveal that the fluorinated PEEK can enhance the osseointegration and bacteriostasis, which provides a potential candidate for dental implants. © 2017 American Chemical Society. |
| 源URL | [http://ir.sic.ac.cn/handle/331005/25882]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; 2.State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China; 3.University of Chinese Academy of Science, Beijing; 100049, China |
| 推荐引用方式 GB/T 7714 | Chen, Meiling,Ouyang, Liping,Lu, Tao,et al. Enhanced Bioactivity and Bacteriostasis of Surface Fluorinated Polyetheretherketone[J]. ACS Applied Materials and Interfaces,2017,9(20):16824-16833. |
| APA | Chen, Meiling.,Ouyang, Liping.,Lu, Tao.,Wang, Heying.,Meng, Fanhao.,...&Liu, Xuanyong.(2017).Enhanced Bioactivity and Bacteriostasis of Surface Fluorinated Polyetheretherketone.ACS Applied Materials and Interfaces,9(20),16824-16833. |
| MLA | Chen, Meiling,et al."Enhanced Bioactivity and Bacteriostasis of Surface Fluorinated Polyetheretherketone".ACS Applied Materials and Interfaces 9.20(2017):16824-16833. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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