Si-doped porous TiO2coatings enhanced in vitro angiogenic behavior of human umbilical vein endothelial cells
文献类型：期刊论文
| 作者 | Ding, Zhihong1,2; Qiao, Yuqin3; Peng, Feng3; Xia, Chao3; Qian, Shi3; Wang, Tao1; Sun, Junying1; Liu, Xuanyong3 |
| 刊名 | Colloids and Surfaces B: Biointerfaces
 |
| 出版日期 | 2017 |
| 卷号 | 159页码:493-500 |
| ISSN号 | 09277765 |
| DOI | 10.1016/j.colsurfb.2017.08.010 |
| 英文摘要 | Recent evidence demonstrates that vessel involvement is crucial in various bone remodeling situations, indicating that blood vessel formation within or surrounding the implant is essential for establishment of rigid implant fixation. In this work, the ability of the silicon-doped porous TiO2coatings fabricated via plasma electrolyte oxidation method (PEO) to enhance the angiogenic potential of human umbilical vein endothelial cells (HUVECs) were investigated. The cellular responses of HUVECs on the silicon-doped porous TiO2coatings were studied through cell proliferation, vascular endothelial growth factor (VEGF) secretion, and angiogenic-associated gene (VEGF, HIF-1α and HGF) expression analysis. The results show that small amount of silicon significantly enhanced angiogenic activity of HUVECs, while larger amount of silicon appears excessive. Hence, the silicon-doped TiO2coating offers a potential solution to improve bone vascularization to achieve efficient osseointegration and restoration of function after implantation. © 2017 Elsevier B.V. |
| 源URL | [http://ir.sic.ac.cn/handle/331005/25689]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Street, Suzhou; Jiangsu; 215006, China; 2.Department of Orthopedics Shanghai Pudong New Area Gongli Hospital, Shanghai; 200135, China; 3.State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China |
| 推荐引用方式 GB/T 7714 | Ding, Zhihong,Qiao, Yuqin,Peng, Feng,et al. Si-doped porous TiO2coatings enhanced in vitro angiogenic behavior of human umbilical vein endothelial cells[J]. Colloids and Surfaces B: Biointerfaces,2017,159:493-500. |
| APA | Ding, Zhihong.,Qiao, Yuqin.,Peng, Feng.,Xia, Chao.,Qian, Shi.,...&Liu, Xuanyong.(2017).Si-doped porous TiO2coatings enhanced in vitro angiogenic behavior of human umbilical vein endothelial cells.Colloids and Surfaces B: Biointerfaces,159,493-500. |
| MLA | Ding, Zhihong,et al."Si-doped porous TiO2coatings enhanced in vitro angiogenic behavior of human umbilical vein endothelial cells".Colloids and Surfaces B: Biointerfaces 159(2017):493-500. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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