Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium
文献类型：期刊论文
| 作者 | Qiu, Jiajun1,3; Geng, Hao1,3; Wang, Donghui1,3; Qian, Shi1; Zhu, Hongqin1; Qiao, Yuqin1; Qian, Wenhao2; Liu, Xuanyong1 |
| 刊名 | ACS Applied Materials and Interfaces
 |
| 出版日期 | 2017 |
| 卷号 | 9期号:14页码:12253-12263 |
| ISSN号 | 19448244 |
| DOI | 10.1021/acsami.7b00314 |
| 英文摘要 | Graphene oxide has attracted widespread attention in the biomedical fields due to its excellent biocompatibility. Herein we investigated the layer-number dependent antibacterial and osteogenic behaviors of graphene oxide in biointerfaces. Graphene oxide with different layer numbers was deposited on the titanium surfaces by cathodal electrophoretic deposition with varied deposition voltages. The initial cell adhesion and spreading, cell proliferation, and osteogenic differentiation were observed from all the samples using rat bone mesenchymal stem cells. Both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus were used to investigate the antibacterial effect of the modified titanium surfaces. Cocultures of human gingival fibroblasts (HGF) cells with Escherichia coli and Staphylococcus aureus were conducted to simulate the conditions of the clinical practice. The results show that the titanium surfaces with graphene oxide exhibited excellent antibacterial and osteogenic effects. Increasing the layer-number of graphene oxide resulted in the augment of reactive oxygen species levels and the wrinkling, which led to the antibacterial and osteogenic effects, respectively. Compared to pure titanium surface in the cells-bacteria coculture process, the modified titanium surfaces with graphene oxide exhibited higher surface coverage percentage of cells. © 2017 American Chemical Society. |
| 源URL | [http://ir.sic.ac.cn/handle/331005/25651]  |
| 专题 | 中国科学院上海硅酸盐研究所 |
| 作者单位 | 1.State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China; 2.Shanghai Xuhui District Dental Center, Shanghai; 200032, China; 3.University of Chinese Academy of Sciences, Beijing; 100049, China |
| 推荐引用方式 GB/T 7714 | Qiu, Jiajun,Geng, Hao,Wang, Donghui,et al. Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium[J]. ACS Applied Materials and Interfaces,2017,9(14):12253-12263. |
| APA | Qiu, Jiajun.,Geng, Hao.,Wang, Donghui.,Qian, Shi.,Zhu, Hongqin.,...&Liu, Xuanyong.(2017).Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium.ACS Applied Materials and Interfaces,9(14),12253-12263. |
| MLA | Qiu, Jiajun,et al."Layer-Number Dependent Antibacterial and Osteogenic Behaviors of Graphene Oxide Electrophoretic Deposited on Titanium".ACS Applied Materials and Interfaces 9.14(2017):12253-12263. |
入库方式： OAI收割
来源：上海硅酸盐研究所
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