Ultrasmall CuCo2S4Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors
文献类型:期刊论文
作者 | Li, Bo1,2; Yuan, Fukang1,3; He, Guanjie4; Han, Xiaoyu4; Wang, Xin1; Qin, Jinbao1; Guo, Zheng Xiao4; Lu, Xinwu1; Wang, Qian5; Parkin, Ivan P.4 |
刊名 | Advanced Functional Materials
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出版日期 | 2017 |
卷号 | 27期号:10 |
ISSN号 | 1616301X |
DOI | 10.1002/adfm.201606218 |
英文摘要 | Copper-based ternary bimetal chalcogenides have very promising potential as multifunctional theragnosis nanoplatform for photothermal treatment of tumors. However, the design and synthesis of such an effective platform remains challenging. In this study, hydrophilic CuCo2S4nanocrystals (NCs) with a desirable size of ≈10 nm are synthesized by a simple one-pot hydrothermal route. The as-prepared ultrasmall CuCo2S4NCs show: 1) intense near-infrared absorption, which is attributed to 3d electronic transitions from the valence band to an intermediate band, as identified by density functional theory calculations; 2) high photothermal performance with a photothermal conversion efficiency up to 73.4%; and 3) capability for magnetic resonance (MR) imaging, as a result of the unpaired 3d electrons of cobalt. Finally, it is demonstrated that the CuCo2S4NCs are a promising “all-in-one” photothermal theragnosis nanoplatform for photothermal cancer therapy under the irradiation of a 915 nm laser at a safe power density of 0.5 W cm−2, guided by MR and infrared thermal imaging. This work further promotes the potential applications of ternary bimetal chalcogenides for photothermal theragnosis therapy. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
源URL | [http://ir.sic.ac.cn/handle/331005/25579] ![]() |
专题 | 中国科学院上海硅酸盐研究所 |
作者单位 | 1.Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai; 200011, China; 2.State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China; 3.Department of Vascular Surgery, Xuzhou Central Hospital, Xuzhou; Jiangsu; 221009, China; 4.Christopher Ingold Laboratory, Department of Chemistry, University College London, London; WC1H 0AJ, United Kingdom; 5.Department of Orthopaedics, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai; 200080, China |
推荐引用方式 GB/T 7714 | Li, Bo,Yuan, Fukang,He, Guanjie,et al. Ultrasmall CuCo2S4Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors[J]. Advanced Functional Materials,2017,27(10). |
APA | Li, Bo.,Yuan, Fukang.,He, Guanjie.,Han, Xiaoyu.,Wang, Xin.,...&Wu, Chengtie.(2017).Ultrasmall CuCo2S4Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors.Advanced Functional Materials,27(10). |
MLA | Li, Bo,et al."Ultrasmall CuCo2S4Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors".Advanced Functional Materials 27.10(2017). |
入库方式: OAI收割
来源:上海硅酸盐研究所
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