Facile synthesis of 1,4-diketones via three-component reactions of alpha-ketoaldehyde, 1,3-dicarbonyl compound, and a nucleophile in water
文献类型：期刊论文
| 作者 | Yang, Jian1; Mei, Fuming1; Fu, Shitao1; Gu YL(顾彦龙)1,2; Gu YL(顾彦龙) |
| 刊名 | Green Chemistry
 |
| 出版日期 | 2018 |
| 卷号 | 20期号:6页码:1367-1374 |
| ISSN号 | 1463-9262 |
| DOI | 10.1039/c7gc03644b |
| 英文摘要 | Three-component reactions of alkylglyoxals, 1,3-dicarbonyl compounds, and a nucleophile were performed under aqueous and catalyst-free conditions, which produced 1,4-diketone scaffolds in a straightforward way. Many compounds, such as indole, azaindole, pyrrole, 2-methylfuran, N,N-dimethylaniline, N-methylaniline, thiophenol, and benzyl mercaptan, were all able to act as nucleophiles to react with alkylglyoxal and 1,3-dicarbonyl compounds. The mechanim of this reaction was also investigated. The obtained 1,4-diketones can be easily converted to many valuable chemicals. |
| 学科主题 | 物理化学与绿色催化 |
| 语种 | 英语 |
| WOS记录号 | WOS:000428088400025 |
| 资助机构 | the National Natural Science Foundation of China (21761132014;21373093);the Fundamental Research Funds for the Central Universities of China (2016YXZD033) ;The Cooperative Innovation Center of Hubei Province;National Science and Technology Support Program (2105BAD21B05-1) |
| 源URL | [http://210.77.64.217/handle/362003/23681]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 通讯作者 | Fu, Shitao; Gu YL(顾彦龙) |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Key Lab Mat Chem Energy Convers & Storage, Hubei Key Lab Mat Chem & Serv Failure, Minist Educ,Sch Chem & Chem Engn, 1037 Luoyu Rd, Wuhan 430074, Peoples R China 2.Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jian,Mei, Fuming,Fu, Shitao,et al. Facile synthesis of 1,4-diketones via three-component reactions of alpha-ketoaldehyde, 1,3-dicarbonyl compound, and a nucleophile in water[J]. Green Chemistry,2018,20(6):1367-1374. |
| APA | Yang, Jian,Mei, Fuming,Fu, Shitao,Gu YL,&顾彦龙.(2018).Facile synthesis of 1,4-diketones via three-component reactions of alpha-ketoaldehyde, 1,3-dicarbonyl compound, and a nucleophile in water.Green Chemistry,20(6),1367-1374. |
| MLA | Yang, Jian,et al."Facile synthesis of 1,4-diketones via three-component reactions of alpha-ketoaldehyde, 1,3-dicarbonyl compound, and a nucleophile in water".Green Chemistry 20.6(2018):1367-1374. |
入库方式： OAI收割
来源：兰州化学物理研究所
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