Genetic Adaptation of Giant Lobelias (Lobelia aberdarica and Lobelia telekil) to Different Altitudes in East African Mountains
文献类型：期刊论文
| 作者 | Zhao, Shu-Ying1,2; Chen, Ling-Yun1,2; Muchuku, John K.1,2; Hu, Guang-Wan2; Wang, Qing-Feng1,2 |
| 刊名 | FRONTIERS IN PLANT SCIENCE
 |
| 出版日期 | 2016-04-12 |
| 卷号 | 7页码:9 |
| 关键词 | dN/dS ratio (omega) giant lobelias natural selection RNA-Seq high altitude |
| ISSN号 | 1664-462X |
| DOI | 10.3389/fpls.2016.00488 |
| 英文摘要 | The giant lobelias in East African mountains are good models for studying molecular mechanisms of adaptation to different altitudes. In this study, we generated RNA-seq data of a middle-altitude species Lobelia aberdarica and a high-altitude species L. telekil, followed by selective pressure estimation of their orthologous genes. Our aim was to explore the important genes potentially involved in adaptation to different altitudes. About 9.3 Gb of clean nucleotides, 167,929-170,534 unigenes with total lengths of 159,762,099-171,138,936 bp for each of the two species were generated. OrthoMCL method identified 3,049 1:1 orthologous genes (each species was represented by one ortholog). Estimations of non-synonymous to synonymous rate were performed using an approximate method and a maximum likelihood method in PAML. Eighty-five orthologous genes were under positive selection. At least 8 of these genes are possibly involved in DNA repair, response to DNA damage and temperature stimulus, and regulation of gene expression, which hints on how giant lobelias adapt to high altitudinal environment that characterized by cold, low oxygen, and strong ultraviolet radiation. The negatively selected genes are over-represented in Gene Ontology terms of hydrolase, macromolecular complex assembly among others. This study sheds light on understanding the molecular mechanism of adaptation to different altitudes, and provides genomic resources for further studies of giant lobelias. |
| 资助项目 | National Natural Science Foundation of China[31500192] ; Chinese Academy of Sciences[XDAO5090305] ; Special Foundation for State Basic Working Program of China[2013PY112300] |
| WOS研究方向 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000373871700001 |
| 出版者 | FRONTIERS MEDIA SA |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/84]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Chen, Ling-Yun; Wang, Qing-Feng |
| 作者单位 | 1.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Aquat Bot & Watershed Ecol, Wuhan, Peoples R China 2.Chinese Acad Sci, Sino Africa Joint Res Ctr, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Shu-Ying,Chen, Ling-Yun,Muchuku, John K.,et al. Genetic Adaptation of Giant Lobelias (Lobelia aberdarica and Lobelia telekil) to Different Altitudes in East African Mountains[J]. FRONTIERS IN PLANT SCIENCE,2016,7:9. |
| APA | Zhao, Shu-Ying,Chen, Ling-Yun,Muchuku, John K.,Hu, Guang-Wan,&Wang, Qing-Feng.(2016).Genetic Adaptation of Giant Lobelias (Lobelia aberdarica and Lobelia telekil) to Different Altitudes in East African Mountains.FRONTIERS IN PLANT SCIENCE,7,9. |
| MLA | Zhao, Shu-Ying,et al."Genetic Adaptation of Giant Lobelias (Lobelia aberdarica and Lobelia telekil) to Different Altitudes in East African Mountains".FRONTIERS IN PLANT SCIENCE 7(2016):9. |
入库方式： OAI收割
来源：武汉植物园
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