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Studies on Transition Metal-Quercetin Complexes Using Electrospray Ionization Tandem Mass Spectrometry
文献类型：期刊论文
| 作者 | Liu, Yuanzhen2; Guo, Mingquan1,2 |
| 刊名 | MOLECULES
 |
| 出版日期 | 2015-05-01 |
| 卷号 | 20期号:5页码:8583-8594 |
| 关键词 | flavonoid ESI-MSn metal complexes CID fragmentation mechanism |
| ISSN号 | 1420-3049 |
| DOI | 10.3390/molecules20058583 |
| 英文摘要 | To systematically study the effects of the number of d electrons of the first transition metal ions (Fe, Co, Ni, Cu and Zn) on the formation and stability of metal flavonoid complexes, we took the quercetin/M2+ complex as a model system to investigate the structures and properties of these complexes. Based on considerable structural information obtained through ESI-MSn, all of the first transition metal ions (Fe2+, Co2+, Ni2+, Cu2+ and Zn2+) were found to form different complexes with quercetin, while with the number of chelating flavonoids decreasing along with the reduction of the metal ionic radius. Quercetin forms different complexes with the above metal divalent ions through its 5-OH and 4-carbonyl groups; the complex stability is highly dependent on both the metallic ion and the flavonoid chelator itself. As for the central ion (M2+), when chelated with quercetin to form the complex, the stability of the complex decreased in the following order: Cu2+ > Ni2+ > Co2+ > Fe2+ > Zn2+. With flavonoid: metal stoichiometries at 2:1, the complexes formed between quercetin and metal ions (Fe2+, Ni2+, Co2+ and Zn2+) have the similar fragmentation mechanism, while Cu2+ displayed different fragmentation mechanism due to the concurrent oxidation. |
| 资助项目 | Chinese Academy of Sciences[29Y429291a0129] ; Sino-Africa joint research project[23Y323751a0275] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000357157600068 |
| 出版者 | MDPI AG |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/266]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Guo, Mingquan |
| 作者单位 | 1.Univ So Calif, Keck Sch Med, Los Angeles, CA 90089 USA 2.Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yuanzhen,Guo, Mingquan. Studies on Transition Metal-Quercetin Complexes Using Electrospray Ionization Tandem Mass Spectrometry[J]. MOLECULES,2015,20(5):8583-8594. |
| APA | Liu, Yuanzhen,&Guo, Mingquan.(2015).Studies on Transition Metal-Quercetin Complexes Using Electrospray Ionization Tandem Mass Spectrometry.MOLECULES,20(5),8583-8594. |
| MLA | Liu, Yuanzhen,et al."Studies on Transition Metal-Quercetin Complexes Using Electrospray Ionization Tandem Mass Spectrometry".MOLECULES 20.5(2015):8583-8594. |
入库方式： OAI收割
来源：武汉植物园
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