The role of glutathione metabolism in tolerance of tobacco BY-2 suspension cells to microcystin-RR
文献类型：期刊论文
| 作者 | Li, Dun Hai3; Huang, Wen Min1,3; Xing, Wei2; Liu, Yong Ding3 |
| 刊名 | BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
 |
| 出版日期 | 2008-03-01 |
| 卷号 | 80期号:3页码:215-219 |
| 关键词 | Microcystin-RR tobacco BY-2 suspension cells glutathione metabolism oxidative stress |
| ISSN号 | 0007-4861 |
| DOI | 10.1007/s00128-007-9348-7 |
| 英文摘要 | This study was undertaken to investigate the role of the glutathione-involved detoxifying mechanism in defending the tobacco BY-2 suspension cells against microcystin-RR (MC-RR). Analysis showed that exposure of the cells to different concentrations of MC-RR (0.1, 1 and 10 mu g/mL) for 0-6 days resulted in a time and concentration-dependent decrease in cell viability and increase in reactive oxygen species (ROS) content. Reduced glutathione (GSH) and total glutathione (tGSH) content as well as glutathione reductase (GR), glutathione peroxidase (GPX) and glutathione-S-transferase (GST) activities significantly increased after 3-4 days exposure in the highest two concentration treated groups, while decreased until reaching the control values except for GPX at day 6. Oxidized glutathione (GSSG) content markedly increased compared with control in high concentration MC-RR treated group after 6 days exposure. The GSH/GSSG ratio was much higher than control in 10 mu g/mL MC-RR treated group at day 4, but after 6 days exposure, the ratios in all treated groups were lower than that of the control group. |
| WOS研究方向 | Environmental Sciences & Ecology ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000253993500008 |
| 出版者 | SPRINGER |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/1104]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Liu, Yong Ding |
| 作者单位 | 1.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Wuhan Bot Garden, Wuhan 430074, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Dun Hai,Huang, Wen Min,Xing, Wei,et al. The role of glutathione metabolism in tolerance of tobacco BY-2 suspension cells to microcystin-RR[J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,2008,80(3):215-219. |
| APA | Li, Dun Hai,Huang, Wen Min,Xing, Wei,&Liu, Yong Ding.(2008).The role of glutathione metabolism in tolerance of tobacco BY-2 suspension cells to microcystin-RR.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,80(3),215-219. |
| MLA | Li, Dun Hai,et al."The role of glutathione metabolism in tolerance of tobacco BY-2 suspension cells to microcystin-RR".BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 80.3(2008):215-219. |
入库方式： OAI收割
来源：武汉植物园
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