Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius
文献类型：期刊论文
| 作者 | Jin, Qinghao1,3; Lee, Jin Woo1; Jang, Hari1; Choi, Ji Eun1; Kim, Hyung Sik1; Lee, Dongho2; Hong, Jin Tae1; Lee, Mi Kyeong1; Hwang, Bang Yeon1 |
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2016-12-15 |
| 卷号 | 26期号:24页码:5995-5998 |
| 关键词 | Echinops latifolius Asteraceae Anti-inflammatory Dimeric sesquiterpene Thiophene |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmcl.2016.10.017 |
| 英文摘要 | Phytochemical investigation of the roots of Echinops latifolius led to the isolation of a new carbon skeleton dimeric sesquiterpene (1) and a new thiophene (2), along with six known compounds (3-8). Their structures and relative stereochemistry were elucidated by spectroscopic and spectrometric methods (H-1 and C-13 NMR, COSY, HSQC, HMBC, ROESY, and MS). All isolates were evaluated for their inhibition of LPS-induced NO production in RAW 264.7 cells. Compounds 4 and 5 exhibited the most potent inhibitory effects on NO production. (C) 2016 Elsevier Ltd. All rights reserved. |
| 资助项目 | Medical Research Center Program (MRC) through the National Research Foundation of Korea[2008-0062275] |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000389784500032 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://202.127.146.157/handle/2RYDP1HH/3057]  |
| 专题 | 中国科学院武汉植物园 |
| 通讯作者 | Hwang, Bang Yeon |
| 作者单位 | 1.Chungbuk Natl Univ, Coll Pharm, Cheongju 28644, South Korea 2.Korea Univ, Coll Life Sci & Biotechnol, Seoul 02841, South Korea 3.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Qinghao,Lee, Jin Woo,Jang, Hari,et al. Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2016,26(24):5995-5998. |
| APA | Jin, Qinghao.,Lee, Jin Woo.,Jang, Hari.,Choi, Ji Eun.,Kim, Hyung Sik.,...&Hwang, Bang Yeon.(2016).Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,26(24),5995-5998. |
| MLA | Jin, Qinghao,et al."Dimeric sesquiterpene and thiophenes from the roots of Echinops latifolius".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26.24(2016):5995-5998. |
入库方式： OAI收割
来源：武汉植物园
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