中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC

文献类型:期刊论文

作者Lu, ZR; Zhuo, RX; Yin, C; Zhou, JW
刊名CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
出版日期1996
卷号17期号:1页码:24-26
关键词aspartic acid derivative cystine derivative Gd(III) complex relaxivity
ISSN号0251-0790
英文摘要Two amino acid derivative ligands, ethylenediamine-N,N'-disuccinic acid(EDDS) and N,N,N',N'-tetrahydroxyethylcystine (THEC), were synthesized from the reaction of L-aspartic acid with 1,2-dibromoethane and L-cystine with chloroethanol respectively. Their paramagnetic gadolinium (III) complexes were prepared by the reaction of the ligands with Gd2O3 and Gd(OAc)(3) respectively. The ligands and their Gd(III) complexes were characterized by IR, H-1 NMR spectroscopy and elemental analysis. The proton relaxivity of the complexes was investigated, and the R(1) values of Gd(III)-EDDS and Gd(III)-THEC are 10.33 and 6.62 mmol(-1). L . s(-1), respectively.
WOS研究方向Chemistry
语种英语
WOS记录号WOS:A1996TT44900007
出版者HIGHER EDUCATION PRESS
源URL[http://202.127.146.157/handle/2RYDP1HH/4115]  
专题中国科学院武汉植物园
通讯作者Lu, ZR
作者单位CHINESE ACAD SCI,WUHAN INST PHYS,WUHAN,PEOPLES R CHINA
推荐引用方式
GB/T 7714
Lu, ZR,Zhuo, RX,Yin, C,et al. Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,1996,17(1):24-26.
APA Lu, ZR,Zhuo, RX,Yin, C,&Zhou, JW.(1996).Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,17(1),24-26.
MLA Lu, ZR,et al."Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 17.1(1996):24-26.

入库方式: OAI收割

来源:武汉植物园

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