Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC
文献类型:期刊论文
作者 | Lu, ZR; Zhuo, RX; Yin, C; Zhou, JW |
刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
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出版日期 | 1996 |
卷号 | 17期号:1页码:24-26 |
关键词 | aspartic acid derivative cystine derivative Gd(III) complex relaxivity |
ISSN号 | 0251-0790 |
英文摘要 | Two amino acid derivative ligands, ethylenediamine-N,N'-disuccinic acid(EDDS) and N,N,N',N'-tetrahydroxyethylcystine (THEC), were synthesized from the reaction of L-aspartic acid with 1,2-dibromoethane and L-cystine with chloroethanol respectively. Their paramagnetic gadolinium (III) complexes were prepared by the reaction of the ligands with Gd2O3 and Gd(OAc)(3) respectively. The ligands and their Gd(III) complexes were characterized by IR, H-1 NMR spectroscopy and elemental analysis. The proton relaxivity of the complexes was investigated, and the R(1) values of Gd(III)-EDDS and Gd(III)-THEC are 10.33 and 6.62 mmol(-1). L . s(-1), respectively. |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:A1996TT44900007 |
出版者 | HIGHER EDUCATION PRESS |
源URL | [http://202.127.146.157/handle/2RYDP1HH/4115] ![]() |
专题 | 中国科学院武汉植物园 |
通讯作者 | Lu, ZR |
作者单位 | CHINESE ACAD SCI,WUHAN INST PHYS,WUHAN,PEOPLES R CHINA |
推荐引用方式 GB/T 7714 | Lu, ZR,Zhuo, RX,Yin, C,et al. Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,1996,17(1):24-26. |
APA | Lu, ZR,Zhuo, RX,Yin, C,&Zhou, JW.(1996).Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,17(1),24-26. |
MLA | Lu, ZR,et al."Synthesis and proton relaxivity of Gd-EDDS and Gd-THEC".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 17.1(1996):24-26. |
入库方式: OAI收割
来源:武汉植物园
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