中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants

文献类型:期刊论文

作者Li, Na3; Guo, Ming-Quan2,4; Zhu, Ming-Zhi1,2,3; Chen, Gui-Lin2,4; Wu, Jian-Lin3; Liu, Zhong-Hua1
刊名PHYTOCHEMICAL ANALYSIS
出版日期2018-07-01
卷号29期号:4页码:365-374
ISSN号0958-0344
关键词ambient ionisation MS mass spectral database medicinal plants MS multiple-dimensional chromatography
DOI10.1002/pca.2763
英文摘要IntroductionMedicinal plants are gaining increasing attention worldwide due to their empirical therapeutic efficacy and being a huge natural compound pool for new drug discovery and development. The efficacy, safety and quality of medicinal plants are the main concerns, which are highly dependent on the comprehensive analysis of chemical components in the medicinal plants. With the advances in mass spectrometry (MS) techniques, comprehensive analysis and fast identification of complex phytochemical components have become feasible, and may meet the needs, for the analysis of medicinal plants. ObjectiveOur aim is to provide an overview on the latest developments in MS and its hyphenated technique and their applications for the comprehensive analysis of medicinal plants. MethodologyApplication of various MS and its hyphenated techniques for the analysis of medicinal plants, including but not limited to one-dimensional chromatography, multiple-dimensional chromatography coupled to MS, ambient ionisation MS, and mass spectral database, have been reviewed and compared in this work. ResultsRecent advancs in MS and its hyphenated techniques have made MS one of the most powerful tools for the analysis of complex extracts from medicinal plants due to its excellent separation and identification ability, high sensitivity and resolution, and wide detection dynamic range. ConclusionTo achieve high-throughput or multi-dimensional analysis of medicinal plants, the state-of-the-art MS and its hyphenated techniques have played, and will continue to play a great role in being the major platform for their further research in order to obtain insight into both their empirical therapeutic efficacy and quality control. The efficacy, safety and quality of medicinal plants are highly dependent on the comprehensive analysis of their chemical components;The latest developments in MS and its hyphenated technique and their applications for the comprehensive analysis of medicinal plants have been reviewed; To achieve high-throughput or multi-dimensional analysis of medicinal plants, MS and its hyphenated techniques have played, and will continue to play a great role.
资助项目Chinese Academy of Sciences[Y429291a01] ; Major Project for Special Technology Innovation of Hubei Province -- Sino-foreign Cooperation Project[2017AHB054] ; National Natural Science Foundation of China[81673580]
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences ; Chemistry
语种英语
出版者WILEY
WOS记录号WOS:000435641700005
源URL[http://202.127.146.157/handle/2RYDP1HH/5469]  
专题中国科学院武汉植物园
通讯作者Guo, Ming-Quan
作者单位1.Hunan Agr Univ, Minist Educ, Key Lab Tea Sci, Changsha, Hunan, Peoples R China
2.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan 430074, Hubei, Peoples R China
3.Macau Univ Sci & Technol, State Key Lab Qual Res Chinese Med, Taipa, Macao, Peoples R China
4.Chinese Acad Sci, Sino Africa Joint Res Ctr, Wuhan, Hubei, Peoples R China
推荐引用方式
GB/T 7714
Li, Na,Guo, Ming-Quan,Zhu, Ming-Zhi,et al. Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants[J]. PHYTOCHEMICAL ANALYSIS,2018,29(4):365-374.
APA Li, Na,Guo, Ming-Quan,Zhu, Ming-Zhi,Chen, Gui-Lin,Wu, Jian-Lin,&Liu, Zhong-Hua.(2018).Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants.PHYTOCHEMICAL ANALYSIS,29(4),365-374.
MLA Li, Na,et al."Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants".PHYTOCHEMICAL ANALYSIS 29.4(2018):365-374.

入库方式: OAI收割

来源:武汉植物园

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