Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography
文献类型：期刊论文
| 作者 | Xie, CH; Hu, JW; Xiao, H; Su, XY; Dong, J; Tian, RJ; He, ZK; Zou, HF |
| 刊名 | journal of separation science
 |
| 出版日期 | 2005-05-01 |
| 卷号 | 28期号:8页码:751-756 |
| 关键词 | electrochromatography silica monolith strong cation-exchange basic pharmaceuticals |
| ISSN号 | 1615-9306 |
| 产权排序 | 1;1 |
| 通讯作者 | 邹汉法 |
| 英文摘要 | a monolithic silica based strong cation-exchange stationary phase was successfully prepared for capillary electrochromatography. the monolithic silica matrix from a sol-gel process was chemically modified by treatment with 3-mercaptopropyltrimethoxysilane followed by a chemical oxidation procedure to produce the desired function. the strong cation-exchange stationary phase was characterized by its substantial and stable electroosmotic flow (eof), and it was observed that the eof value of the prepared column remained almost unchanged at different buffer ph values and slowly decreased with increasing phosphate concentration in the mobile phase. the monolithic silica column with strong cation-exchange stationary phase has been successfully employed in the electrochromatographic separation of beta-blockers and alkaloids extracted from traditional chinese medicines (tcms). the column efficiencies for the tested beta-blockers varied from 210,000 to 340,000 plates/m. a peak compression effect was observed for atenolol with the mobile phase having a low phosphate concentration. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | urea-hydrogen-peroxide ; dansyl amino-acids ; chromatographic characterization ; trifluoroacetic-anhydride ; pharmaceutical analysis ; liquid-chromatography ; reversed-phase ; separation ; performance ; oxidation |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000229404700007 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/92739]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromoto R&A Ctr, Dalian 116011, Peoples R China 2.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xie, CH,Hu, JW,Xiao, H,et al. Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography[J]. journal of separation science,2005,28(8):751-756. |
| APA | Xie, CH.,Hu, JW.,Xiao, H.,Su, XY.,Dong, J.,...&Zou, HF.(2005).Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography.journal of separation science,28(8),751-756. |
| MLA | Xie, CH,et al."Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography".journal of separation science 28.8(2005):751-756. |
入库方式： OAI收割
来源：大连化学物理研究所
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