Evaluation of nonlinear chromatographic performance by frontal analysis using a simple multi-plate mathematical model
文献类型：期刊论文
| 作者 | Hao, WQ; Wang, JD |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2005-01-21 |
| 卷号 | 1063期号:1-2页码:47-56 |
| 关键词 | frontal analysis multi-plate model equilibrium-dispersive model Thomas model membrane affinity chromatography reversed-phase liquid chromatography bovine serum albumin caffeine |
| 产权排序 | 1;1 |
| 通讯作者 | 王俊德 |
| 英文摘要 | a multi-plate (nip) mathematical model was proposed by frontal analysis to evaluate nonlinear chromatographic performance. one of its advantages is that the parameters may be easily calculated from experimental data. moreover, there is a good correlation between it and the equilibrium-dispersive (e-d) or thomas models. this shows that it can well accommodate both types of band broadening that is comprised of either diffusion-dominated processes or kinetic sorption processes. the mp model can well describe experimental breakthrough curves that were obtained from membrane affinity chromatography and column reversed-phase liquid chromatography. furthermore, the coefficients of mass transfer may be calculated according to the relationship between the mp model and the e-d or thomas models. (c) 2004 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | affinity-membrane bioseparations ; mass-transfer properties ; liquid-chromatography ; ion-exchange ; concentration-dependence ; adsorption-isotherms ; protein adsorption ; sorption kinetics ; stationary phases ; peak asymmetry |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000226299800006 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/93211]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hao, WQ,Wang, JD. Evaluation of nonlinear chromatographic performance by frontal analysis using a simple multi-plate mathematical model[J]. journal of chromatography a,2005,1063(1-2):47-56. |
| APA | Hao, WQ,&Wang, JD.(2005).Evaluation of nonlinear chromatographic performance by frontal analysis using a simple multi-plate mathematical model.journal of chromatography a,1063(1-2),47-56. |
| MLA | Hao, WQ,et al."Evaluation of nonlinear chromatographic performance by frontal analysis using a simple multi-plate mathematical model".journal of chromatography a 1063.1-2(2005):47-56. |
入库方式： OAI收割
来源：大连化学物理研究所
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