Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography
文献类型：期刊论文
| 作者 | Sheng, LH; Li, SL; Kong, L; Chen, XG; Mao, XQ; Su, XY; Zou, HF; Li, P |
| 刊名 | journal of pharmaceutical and biomedical analysis
 |
| 出版日期 | 2005-06-15 |
| 卷号 | 38期号:2页码:216-224 |
| 关键词 | immobilized liposome chromatography compounds interacting with liposome membranes Danggui Buxue decoction Radix Astragli Radix Angelica Sinensis |
| 通讯作者 | 邹汉法 ; 李萍 |
| 产权排序 | 1;1 |
| 英文摘要 | immobilized liposome chromatography (ilc), the stationary phase of which has been regarded as a mimic biomembranes system was used to separate and analyze compounds interacting with liposome membrane in danggui buxue decoction, a combined prescription of traditional chinese medicines (cptcms), and its compositions radix astragli and radix angelica sinensis. more than 10 main peaks in the extract of danggui buxue decoction were resolved on the ilc column, suggesting that more than 10 components in the prescription have significant retention on ilc column. ligustilide, astragaloside, tv and formononetin, three main bioactive ingredients in danggui buxue decoction, were found to have relatively significant, while ferulic acid, another bioactive ingredient in the prescription, relatively weak retention on ilc column. effects of the eluent ph and amount of immobilized phosphatidylcholine (pc) on separation of interactional compounds in the extract of danggui buxue decoction were also investigated. it was found that these two factors strongly affected the retention of some interactional compounds. in addition, the fractions partitioned with different solvents from water extract of this combined prescription were evaluated with this ilc column system. (c) 2005 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine |
| 类目[WOS] | chemistry, analytical ; pharmacology & pharmacy |
| 研究领域[WOS] | chemistry ; pharmacology & pharmacy |
| 关键词[WOS] | liquid-chromatography ; angelica-sinensis ; biomembrane chromatography ; unilamellar liposomes ; mass-spectrometry ; herbal medicines ; drugs ; permeability ; ligustilide ; model |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000230217600004 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/93377]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China 2.China Pharmaceut Univ, Key Lab Modern Chinese Med, Nanjing 210009, Peoples R China 3.China Pharmaceut Univ, Dept Pharmacognosy, Nanjing 210009, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sheng, LH,Li, SL,Kong, L,et al. Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography[J]. journal of pharmaceutical and biomedical analysis,2005,38(2):216-224. |
| APA | Sheng, LH.,Li, SL.,Kong, L.,Chen, XG.,Mao, XQ.,...&Li, P.(2005).Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography.journal of pharmaceutical and biomedical analysis,38(2),216-224. |
| MLA | Sheng, LH,et al."Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography".journal of pharmaceutical and biomedical analysis 38.2(2005):216-224. |
入库方式： OAI收割
来源：大连化学物理研究所
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