Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi
文献类型：期刊论文
| 作者 | Han, QB; Wang, YL; Yang, L; Tso, TF; Qiao, CF; Song, JZ; Xu, LJ; Chen, SL; Yang, DJ; Xu, HX |
| 刊名 | chemical & pharmaceutical bulletin
 |
| 出版日期 | 2006-02-01 |
| 卷号 | 54期号:2页码:265-267 |
| 关键词 | Garcinia hanburyi cytotoxicity xanthone multidrug resistance gaudichaudic acid isogambogenic acid |
| 产权排序 | 2;2 |
| 通讯作者 | hong-xi xu |
| 英文摘要 | thirteen xanthones (1-13) were isolated from the resin of garcinia hanburyi. among them, two new compounds (namely gaudichaudic acid, and isogambogenic acid, 1, 2), and one new natural product (deoxygaudichaudione a, 3) were identified on the basis of extensive spectral evidence including detailed 2d nmr data. ten of these xanthones were tested for their cytotoxicities against human leukemia k562 (k562/s) and doxorubicin-resistant k562 (k562/r) cell lines, and showed similar inhibitory effects on both cell lines, suggesting that this group of polyprenylated xanthones might not be multidrug resistance (mdr) substrates. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | chemistry, medicinal ; chemistry, multidisciplinary ; pharmacology & pharmacy |
| 研究领域[WOS] | pharmacology & pharmacy ; chemistry |
| 关键词[WOS] | gambogic acid ; in-vitro ; cells ; proliferation ; apoptosis ; assay |
| 收录类别 | SCI ; IC |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000235852700027 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/93685]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Hong Kong Jockey Club Inst Chinese Med, Chinese Med Lab, Hong Kong, Hong Kong, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resources Discovery, Dalian 116023, Peoples R China 3.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Han, QB,Wang, YL,Yang, L,et al. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi[J]. chemical & pharmaceutical bulletin,2006,54(2):265-267. |
| APA | Han, QB.,Wang, YL.,Yang, L.,Tso, TF.,Qiao, CF.,...&Xu, HX.(2006).Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi.chemical & pharmaceutical bulletin,54(2),265-267. |
| MLA | Han, QB,et al."Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi".chemical & pharmaceutical bulletin 54.2(2006):265-267. |
入库方式： OAI收割
来源：大连化学物理研究所
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