Parallel analysis of biomolecules on a microfabricated capillary array chip
文献类型：期刊论文
| 作者 | Shen, Z; Liu, XJ; Long, ZC; Liu, DY; Ye, NN; Qin, JH; Dai, ZP; Lin, BC |
| 刊名 | electrophoresis
 |
| 出版日期 | 2006-03-01 |
| 卷号 | 27期号:5-6页码:1084-1092 |
| 关键词 | biological analysis capillary array electrophoresis microfluidic chip |
| 产权排序 | 1;1 |
| 通讯作者 | 林炳承 |
| 英文摘要 | this paper focused on a self-developed microfluiclic array system with microfabricated capillary array electrophoresis (mu-cae) chip for parallel chip electrophoresis of biomolecules. the microfluiclic array layout consists of two common reservoirs coupled to four separation channels connected to sample injection channel on the soda-lime glass substrate. the excitation scheme for distributing a 20 mw laser beam to separation channels in an array is achieved. under the control of program, the sample injection and separation in multichannel can be achieved through six high-voltage modules' output. a ccd camera was used to monitor electrophoretic separations simultaneously in four channels with lif detection, and the electropherograms can be plotted directly without reconstruction by additional software. parallel multichannel electrophoresis of series biomolecules including amino acids, proteins, and nucleic acids was performed on this system and the results showed fine reproducibility. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | total analysis systems ; throughput genetic-analysis ; sample introduction ; electrophoresis ; dna ; microchip ; immunoassay ; technology ; devices ; cells |
| 收录类别 | SCI |
| 原文出处 | true |
| 语种 | 英语 |
| WOS记录号 | WOS:000236511900018 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/93869]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Z,Liu, XJ,Long, ZC,et al. Parallel analysis of biomolecules on a microfabricated capillary array chip[J]. electrophoresis,2006,27(5-6):1084-1092. |
| APA | Shen, Z.,Liu, XJ.,Long, ZC.,Liu, DY.,Ye, NN.,...&Lin, BC.(2006).Parallel analysis of biomolecules on a microfabricated capillary array chip.electrophoresis,27(5-6),1084-1092. |
| MLA | Shen, Z,et al."Parallel analysis of biomolecules on a microfabricated capillary array chip".electrophoresis 27.5-6(2006):1084-1092. |
入库方式： OAI收割
来源：大连化学物理研究所
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