Simulated microgravity alters growth and microcystin production in Microcystis aeruginosa (cyanophyta)
文献类型：期刊论文
| 作者 | Xiao, Yuan1,2; Liu, Yongding1; Wang, Gaohong1; Hao, Zongjie1,2; An, Yanjun1,2 |
| 刊名 | TOXICON
 |
| 出版日期 | 2010-08-01 |
| 卷号 | 56期号:1页码:1-7 |
| 关键词 | Simulated microgravity Microcystis aeruginosa Microcystin Secondary metabolism |
| ISSN号 | 0041-0101 |
| 通讯作者 | Liu, YD, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, 7 S Donghu Rd, Wuhan 430072, Hubei, Peoples R China |
| 中文摘要 | Recent researches indicated that microgravity can increase pathogenic bacteria virulence. We presumed that microgravity might affect the toxin production of toxic cyanobacteria too. Microcystis aeruginosa PCC7806 was chosen as the model organism to investigate the effects of simulated microgravity (SMG) on the growth and toxin production of toxic cyanobacteria. SMG could inhibit the growth of M. aeruginosa, which resulted in decreased cell number and lower specific growth rate after 20-day treatment. M. aeruginosa sensed the reduced gravity very quickly and immediately up-regulated its microcystin (MC) synthesis and exudation in 2 days. Subsequently, the intracellular MC content fell back since the 8(th) day and was stable around the initial level in the following days, suggesting a quick adaptation to the reduced gravity. SMG had negative effects on the photochemical system and the absorption of phosphorus in most time. However, the photosynthetic pigment concentrations and nitrogen absorption used to be transitorily stimulated upwards by SMG. It was assumed that SMG inhibited cell growth by interfering its photosynthesis and phosphorus uptake, while the enhanced MC production was related with pigment and nitrogen metabolisms. This study reveals that SMG is a novel environmental signal which inhibits growth and enhances MC production of M. aeruginosa. (C) 2010 Elsevier Ltd. All rights reserved. |
| 英文摘要 | Recent researches indicated that microgravity can increase pathogenic bacteria virulence. We presumed that microgravity might affect the toxin production of toxic cyanobacteria too. Microcystis aeruginosa PCC7806 was chosen as the model organism to investigate the effects of simulated microgravity (SMG) on the growth and toxin production of toxic cyanobacteria. SMG could inhibit the growth of M. aeruginosa, which resulted in decreased cell number and lower specific growth rate after 20-day treatment. M. aeruginosa sensed the reduced gravity very quickly and immediately up-regulated its microcystin (MC) synthesis and exudation in 2 days. Subsequently, the intracellular MC content fell back since the 8(th) day and was stable around the initial level in the following days, suggesting a quick adaptation to the reduced gravity. SMG had negative effects on the photochemical system and the absorption of phosphorus in most time. However, the photosynthetic pigment concentrations and nitrogen absorption used to be transitorily stimulated upwards by SMG. It was assumed that SMG inhibited cell growth by interfering its photosynthesis and phosphorus uptake, while the enhanced MC production was related with pigment and nitrogen metabolisms. This study reveals that SMG is a novel environmental signal which inhibits growth and enhances MC production of M. aeruginosa. (C) 2010 Elsevier Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Pharmacology & Pharmacy; Toxicology |
| 类目[WOS] | Pharmacology & Pharmacy ; Toxicology |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Toxicology |
| 关键词[WOS] | SHEAR MODELED MICROGRAVITY ; BACTERIAL GENE-EXPRESSION ; SPACE-FLIGHT ; MICROALGAE ; VIRULENCE ; NITROGEN ; PCC7806 |
| 收录类别 | SCI |
| 资助信息 | Chinese Manned Space Flight Project ; Natural Science Foundation of China [30970688] |
| 语种 | 英语 |
| WOS记录号 | WOS:000278205500001 |
| 公开日期 | 2010-12-23 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/13703]  |
| 专题 | 水生生物研究所_水环境工程研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiao, Yuan,Liu, Yongding,Wang, Gaohong,et al. Simulated microgravity alters growth and microcystin production in Microcystis aeruginosa (cyanophyta)[J]. TOXICON,2010,56(1):1-7. |
| APA | Xiao, Yuan,Liu, Yongding,Wang, Gaohong,Hao, Zongjie,&An, Yanjun.(2010).Simulated microgravity alters growth and microcystin production in Microcystis aeruginosa (cyanophyta).TOXICON,56(1),1-7. |
| MLA | Xiao, Yuan,et al."Simulated microgravity alters growth and microcystin production in Microcystis aeruginosa (cyanophyta)".TOXICON 56.1(2010):1-7. |
入库方式： OAI收割
来源：水生生物研究所
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