中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria

文献类型:期刊论文

作者Zhang, Defeng1,2; Li, Aihua1; Xie, Jun3; Ji, Cheng1,2
刊名AQUACULTURE RESEARCH
出版日期2010-06-16
卷号41期号:7页码:1095-1100
关键词berberine hydrochloride enrofloxacin fish pathogenic bacteria synergistic effect
ISSN号1355-557X
通讯作者Li, AH, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
中文摘要Berberine the main antibacterial substance in the rhizome of Coptis chinensis Franch, is used as an antimicrobial agent for a long time. This study was carried out to investigate the potential of berberine alone or in combination with enrofloxacin against six common fish pathogens for use in fish disease management in aquaculture. The minimum inhibitory concentrations (MICs) of berberine hydrochloride against Aeromonas hydrophila, Pseudomonas fluorescens, Vibrio vulnificus, Edwardsiella ictaluri, Escherichia coli and Streptococcus agalactiae were determined and to be > 500, > 500, > 500, 300, 400 and 100 mu g mL-1 respectively. The minimal bactericidal concentrations (MBCs) of berberine hydrochloride to E. coli, E. ictaluri and S. agalactiae were 300-500 mu g mL-1. In combination with enrofloxacin, the MICs and MBCs of berberine hydrochloride significantly decreased against E. coli and E. ictaluri but not against Streptococcus dysgalactiae. These results demonstrated that the berberine hydrochloride enhanced the bactericidal effect of enrofloxacin and vice versa. The synergistic bactericidal effect of berberine hydrochloride and enrofloxacin suggest its potential use in fish disease management in aquaculture. This is the first study on the inhibitory effect of berberine hydrochloride against fish pathogenic bacteria.
英文摘要Berberine the main antibacterial substance in the rhizome of Coptis chinensis Franch, is used as an antimicrobial agent for a long time. This study was carried out to investigate the potential of berberine alone or in combination with enrofloxacin against six common fish pathogens for use in fish disease management in aquaculture. The minimum inhibitory concentrations (MICs) of berberine hydrochloride against Aeromonas hydrophila, Pseudomonas fluorescens, Vibrio vulnificus, Edwardsiella ictaluri, Escherichia coli and Streptococcus agalactiae were determined and to be > 500, > 500, > 500, 300, 400 and 100 mu g mL-1 respectively. The minimal bactericidal concentrations (MBCs) of berberine hydrochloride to E. coli, E. ictaluri and S. agalactiae were 300-500 mu g mL-1. In combination with enrofloxacin, the MICs and MBCs of berberine hydrochloride significantly decreased against E. coli and E. ictaluri but not against Streptococcus dysgalactiae. These results demonstrated that the berberine hydrochloride enhanced the bactericidal effect of enrofloxacin and vice versa. The synergistic bactericidal effect of berberine hydrochloride and enrofloxacin suggest its potential use in fish disease management in aquaculture. This is the first study on the inhibitory effect of berberine hydrochloride against fish pathogenic bacteria.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
学科主题Fisheries
类目[WOS]Fisheries
研究领域[WOS]Fisheries
关键词[WOS]ANTIMICROBIAL ACTIVITY ; ESCHERICHIA-COLI ; CANDIDA-ALBICANS ; VIBRIO-CHOLERAE ; SULFATE ; RESISTANT ; DRUGS
收录类别SCI
资助信息National Science and Technology Pillar Programs [2006BAD03B04, 2006BAK02A22]; National Science Foundation of China [30670112]
语种英语
WOS记录号WOS:000278643100017
公开日期2010-12-23
源URL[http://ir.ihb.ac.cn/handle/342005/13609]  
专题水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文
作者单位1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
2.Chinese Acad Sci, Postgrad Sch, Beijing, Peoples R China
3.Chinese Acad Fishery Sci, Minist Agr, Freshwater Fisheries Res Ctr, Wuxi, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Defeng,Li, Aihua,Xie, Jun,et al. In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria[J]. AQUACULTURE RESEARCH,2010,41(7):1095-1100.
APA Zhang, Defeng,Li, Aihua,Xie, Jun,&Ji, Cheng.(2010).In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria.AQUACULTURE RESEARCH,41(7),1095-1100.
MLA Zhang, Defeng,et al."In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria".AQUACULTURE RESEARCH 41.7(2010):1095-1100.

入库方式: OAI收割

来源:水生生物研究所

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