In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria
文献类型：期刊论文
| 作者 | Zhang, Defeng1,2; Li, Aihua1; Xie, Jun3; Ji, Cheng1,2 |
| 刊名 | AQUACULTURE RESEARCH
 |
| 出版日期 | 2010-06-16 |
| 卷号 | 41期号:7页码:1095-1100 |
| 关键词 | berberine hydrochloride enrofloxacin fish pathogenic bacteria synergistic effect |
| ISSN号 | 1355-557X |
| 通讯作者 | Li, AH, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| 中文摘要 | Berberine the main antibacterial substance in the rhizome of Coptis chinensis Franch, is used as an antimicrobial agent for a long time. This study was carried out to investigate the potential of berberine alone or in combination with enrofloxacin against six common fish pathogens for use in fish disease management in aquaculture. The minimum inhibitory concentrations (MICs) of berberine hydrochloride against Aeromonas hydrophila, Pseudomonas fluorescens, Vibrio vulnificus, Edwardsiella ictaluri, Escherichia coli and Streptococcus agalactiae were determined and to be > 500, > 500, > 500, 300, 400 and 100 mu g mL-1 respectively. The minimal bactericidal concentrations (MBCs) of berberine hydrochloride to E. coli, E. ictaluri and S. agalactiae were 300-500 mu g mL-1. In combination with enrofloxacin, the MICs and MBCs of berberine hydrochloride significantly decreased against E. coli and E. ictaluri but not against Streptococcus dysgalactiae. These results demonstrated that the berberine hydrochloride enhanced the bactericidal effect of enrofloxacin and vice versa. The synergistic bactericidal effect of berberine hydrochloride and enrofloxacin suggest its potential use in fish disease management in aquaculture. This is the first study on the inhibitory effect of berberine hydrochloride against fish pathogenic bacteria. |
| 英文摘要 | Berberine the main antibacterial substance in the rhizome of Coptis chinensis Franch, is used as an antimicrobial agent for a long time. This study was carried out to investigate the potential of berberine alone or in combination with enrofloxacin against six common fish pathogens for use in fish disease management in aquaculture. The minimum inhibitory concentrations (MICs) of berberine hydrochloride against Aeromonas hydrophila, Pseudomonas fluorescens, Vibrio vulnificus, Edwardsiella ictaluri, Escherichia coli and Streptococcus agalactiae were determined and to be > 500, > 500, > 500, 300, 400 and 100 mu g mL-1 respectively. The minimal bactericidal concentrations (MBCs) of berberine hydrochloride to E. coli, E. ictaluri and S. agalactiae were 300-500 mu g mL-1. In combination with enrofloxacin, the MICs and MBCs of berberine hydrochloride significantly decreased against E. coli and E. ictaluri but not against Streptococcus dysgalactiae. These results demonstrated that the berberine hydrochloride enhanced the bactericidal effect of enrofloxacin and vice versa. The synergistic bactericidal effect of berberine hydrochloride and enrofloxacin suggest its potential use in fish disease management in aquaculture. This is the first study on the inhibitory effect of berberine hydrochloride against fish pathogenic bacteria. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Fisheries |
| 类目[WOS] | Fisheries |
| 研究领域[WOS] | Fisheries |
| 关键词[WOS] | ANTIMICROBIAL ACTIVITY ; ESCHERICHIA-COLI ; CANDIDA-ALBICANS ; VIBRIO-CHOLERAE ; SULFATE ; RESISTANT ; DRUGS |
| 收录类别 | SCI |
| 资助信息 | National Science and Technology Pillar Programs [2006BAD03B04, 2006BAK02A22]; National Science Foundation of China [30670112] |
| 语种 | 英语 |
| WOS记录号 | WOS:000278643100017 |
| 公开日期 | 2010-12-23 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/13609]  |
| 专题 | 水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Postgrad Sch, Beijing, Peoples R China 3.Chinese Acad Fishery Sci, Minist Agr, Freshwater Fisheries Res Ctr, Wuxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Defeng,Li, Aihua,Xie, Jun,et al. In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria[J]. AQUACULTURE RESEARCH,2010,41(7):1095-1100. |
| APA | Zhang, Defeng,Li, Aihua,Xie, Jun,&Ji, Cheng.(2010).In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria.AQUACULTURE RESEARCH,41(7),1095-1100. |
| MLA | Zhang, Defeng,et al."In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria".AQUACULTURE RESEARCH 41.7(2010):1095-1100. |
入库方式： OAI收割
来源：水生生物研究所
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