Medaka fish stem cells and their applications
文献类型：期刊论文
| 作者 | Yi MeiSheng1; Hong Ni1; Li ZhenDong1; Yan Yan1,2; Wang DanKe1; Zhao HaoBin1,3; Hong YunHan1,4 |
| 刊名 | SCIENCE CHINA-LIFE SCIENCES
 |
| 出版日期 | 2010-04-01 |
| 卷号 | 53期号:4页码:426-434 |
| 关键词 | medaka stem cells pluripotency chimera nuclear transplant semi-cloning |
| ISSN号 | 1674-7305 |
| 通讯作者 | Hong, YH, Natl Univ Singapore, Dept Biol Sci, 10 Kent Ridge Crescent, Singapore 119260, Singapore |
| 中文摘要 | Stem cells are present in developing embryos and adult tissues of multicellular organisms. Owing to their unique features, stem cells provide excellent opportunities for experimental analyses of basic developmental processes such as pluripotency control and cell fate decision and for regenerative medicine by stem cell-based therapy. Stem cell cultures have been best studied in 3 vertebrate organisms. These are the mouse, human and a small laboratory fish called medaka. Specifically, medaka has given rise to the first embryonic stem (ES) cells besides the mouse, the first adult testis-derived male stem cells spermatogonia capable of test-tube sperm production, and most recently, even haploid ES cells capable of producing Holly, a semi-cloned fertile female medaka from a mosaic oocyte created by microinjecting a haploid ES cell nucleus directly into a normal oocyte. These breakthroughs make medaka a favoring vertebrate model for stem cell research, the topic of this review. |
| 英文摘要 | Stem cells are present in developing embryos and adult tissues of multicellular organisms. Owing to their unique features, stem cells provide excellent opportunities for experimental analyses of basic developmental processes such as pluripotency control and cell fate decision and for regenerative medicine by stem cell-based therapy. Stem cell cultures have been best studied in 3 vertebrate organisms. These are the mouse, human and a small laboratory fish called medaka. Specifically, medaka has given rise to the first embryonic stem (ES) cells besides the mouse, the first adult testis-derived male stem cells spermatogonia capable of test-tube sperm production, and most recently, even haploid ES cells capable of producing Holly, a semi-cloned fertile female medaka from a mosaic oocyte created by microinjecting a haploid ES cell nucleus directly into a normal oocyte. These breakthroughs make medaka a favoring vertebrate model for stem cell research, the topic of this review. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Biology |
| 类目[WOS] | Biology |
| 研究领域[WOS] | Life Sciences & Biomedicine - Other Topics |
| 关键词[WOS] | PRIMORDIAL GERM-CELLS ; ORYZIAS-LATIPES ; IN-VITRO ; MOUSE EMBRYOS ; ES CELLS ; KNOCKOUT MICE ; LINE ; ESTABLISHMENT ; GENE ; DIFFERENTIATION |
| 收录类别 | SCI |
| 资助信息 | Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] |
| 语种 | 英语 |
| WOS记录号 | WOS:000277417800005 |
| 公开日期 | 2011-01-20 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/13856]  |
| 专题 | 水生生物研究所_鱼类生物学及渔业生物技术研究中心_期刊论文 |
| 作者单位 | 1.Natl Univ Singapore, Dept Biol Sci, Singapore 119260, Singapore 2.Nanyang Technol Univ, Sch Chem & Biomed Engn, Div Bioengn, Singapore 637457, Singapore 3.Huazhong Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China 4.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yi MeiSheng,Hong Ni,Li ZhenDong,et al. Medaka fish stem cells and their applications[J]. SCIENCE CHINA-LIFE SCIENCES,2010,53(4):426-434. |
| APA | Yi MeiSheng.,Hong Ni.,Li ZhenDong.,Yan Yan.,Wang DanKe.,...&Hong YunHan.(2010).Medaka fish stem cells and their applications.SCIENCE CHINA-LIFE SCIENCES,53(4),426-434. |
| MLA | Yi MeiSheng,et al."Medaka fish stem cells and their applications".SCIENCE CHINA-LIFE SCIENCES 53.4(2010):426-434. |
入库方式： OAI收割
来源：水生生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。