Mechanism of the synergistic toxicity of malononitrile and p-nitrobenzaldehyde with Photobacterium phosphoreum
文献类型：期刊论文
| 作者 | Lin, ZF ; Zhang, WH ; Wang, LS ; Yu, HX ; Wu, CD |
| 刊名 | TOXICOLOGY MECHANISMS AND METHODS
 |
| 出版日期 | 2003 |
| 卷号 | 13期号:4页码:241-245 |
| 关键词 | malononitrile Photobacterium phosphoreum p-nitrobenzaldehyde synergistic toxicity toxicodynamic interactions toxicokinetic interactions |
| ISSN号 | 1537-6524 |
| 中文摘要 | In this study the mechanism of synergistic toxicity between malononitrile and p-nitrobenzaidehyde was revealed by examining their toxicodynamic and toxicokinetic interactions. The investigation of the toxicodynamic interactions focused on the interactions among malononitrile, p-nitrobenzaldehyde, and luciferase, and found that malononitrile does not induce luciferase to bind p-nitrobenzaidehyde. This result suggested that the synergistic toxicity does not arise from toxicodynamic interactions. Further research on toxicokinetic interactions compared the amounts of p-nitrobenzaidehyde being transported from the water phase to the biotic phase in two circumstances-in the presence of malononitrile and in its absence. The results of this research indicated that in the presence of malononitrile, more p-nitrobenzaldehyde is transported, and it is the increased amount of p-nitrobenzaidehyde that leads to the synergistic toxicity of malononitrile and p-nitrobenzaldehyde. |
| 学科主题 | Toxicology |
| 收录类别 | SCI |
| 原文出处 | TAYLOR & FRANCIS INC |
| WOS记录号 | WOS:000186699700001 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5535]  |
| 专题 | 南海海洋研究所_热带海洋环境国家重点实验室(LTO) |
| 推荐引用方式 GB/T 7714 | Lin, ZF,Zhang, WH,Wang, LS,et al. Mechanism of the synergistic toxicity of malononitrile and p-nitrobenzaldehyde with Photobacterium phosphoreum[J]. TOXICOLOGY MECHANISMS AND METHODS,2003,13(4):241-245. |
| APA | Lin, ZF,Zhang, WH,Wang, LS,Yu, HX,&Wu, CD.(2003).Mechanism of the synergistic toxicity of malononitrile and p-nitrobenzaldehyde with Photobacterium phosphoreum.TOXICOLOGY MECHANISMS AND METHODS,13(4),241-245. |
| MLA | Lin, ZF,et al."Mechanism of the synergistic toxicity of malononitrile and p-nitrobenzaldehyde with Photobacterium phosphoreum".TOXICOLOGY MECHANISMS AND METHODS 13.4(2003):241-245. |
入库方式： OAI收割
来源：南海海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。