Reduced cortical thickness in right heschl’s gyrus associated with auditory verbal hallucinations severity in first-episode schizophrenia
文献类型：期刊论文
| 作者 | Chen,Xudong1; Liang,Shengxiang2; Pu,Weidan3; Song,Yinnan2; Mwansisya,Tumbwene E.1,4; Yang,Qing5; Liu,Haihong6; Liu,Zhening1; Shan,Baoci2; Xue,Zhimin1 |
| 刊名 | Bmc psychiatry
 |
| 出版日期 | 2015-07-07 |
| 卷号 | 15期号:1 |
| ISSN号 | 1471-244X |
| 关键词 | Schizophrenia Auditory hallucination Cortical thickness Magnetic resonance imaging Heschl’s gyrus |
| DOI | 10.1186/s12888-015-0546-2 |
| 通讯作者 | Xue,zhimin(x.zhimin@163.com) |
| 英文摘要 | Abstractbackgroundauditory verbal hallucinations (avhs) represent one of the most intriguing phenomena in schizophrenia, however, brain abnormalities underlying avhs remain unclear. the present study examined the association between cortical thickness and avhs in first-episode schizophrenia.methodhigh-resolution mr images were obtained in 49 first-episode schizophrenia (fes) patients and 50 well-matched healthy controls (hcs). among the fes patients, 18 suffered persistent avhs (“auditory hallucination” ah group), and 31 never experienced avhs (“no hallucination” nh group). the severity of avhs was rated by the auditory hallucinations rating scale (ahrs). cortical thickness differences among the three groups and their association with avhs severity were examined.resultscompared to both hcs and nh patients, ah patients showed lower cortical thickness in the right heschl’s gyrus. the degree of reduction in the cortical thickness was correlated with avh severity in the ah patients.conclusionsabnormalities of cortical thickness in the heschl’s gyrus may be a physiological factor underlying auditory verbal hallucinations in schizophrenia. |
| 语种 | 英语 |
| 出版者 | BioMed Central |
| WOS记录号 | BMC:10.1186/S12888-015-0546-2 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2175667 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Xue,Zhimin |
| 作者单位 | 1.Central South University; Mental Health Institute of the Second Xiangya Hospital, Key Laboratory of Psychiatry and Mental Health of Hunan Province 2.Chinese Academy of Sciences; Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics 3.Central South University; Medical Psychological Institute of the Second Xiangya Hospital 4.the University of Dodoma; Department of Clinical Nursing and Community Health 5.Yale-New Haven Hospital, Yale School of Medicine; Department of Medicine 6.Central South University; Mental Health Center of Xiangya Hospital |
| 推荐引用方式 GB/T 7714 | Chen,Xudong,Liang,Shengxiang,Pu,Weidan,et al. Reduced cortical thickness in right heschl’s gyrus associated with auditory verbal hallucinations severity in first-episode schizophrenia[J]. Bmc psychiatry,2015,15(1). |
| APA | Chen,Xudong.,Liang,Shengxiang.,Pu,Weidan.,Song,Yinnan.,Mwansisya,Tumbwene E..,...&Xue,Zhimin.(2015).Reduced cortical thickness in right heschl’s gyrus associated with auditory verbal hallucinations severity in first-episode schizophrenia.Bmc psychiatry,15(1). |
| MLA | Chen,Xudong,et al."Reduced cortical thickness in right heschl’s gyrus associated with auditory verbal hallucinations severity in first-episode schizophrenia".Bmc psychiatry 15.1(2015). |
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来源：高能物理研究所
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