[gd@c-82(oh)(22)](n) nanoparticles inhibit the migration and adhesion of glioblastoma cells
文献类型：期刊论文
| 作者 | Wang, Jing1; Gui, Feng1; Ding, Ting1; Liu, Xiaoli2,3; Xing, Gengmei2,3; Zhao, Yuliang2,3; Zhang, Ning1; Ma, Yongjie1 |
| 刊名 | Oncology letters
 |
| 出版日期 | 2010-07-01 |
| 卷号 | 1期号:4页码:771-775 |
| ISSN号 | 1792-1074 |
| 关键词 | Nanoparticle [gd@c-82(oh)(22)](n) Glioblastoma Migration Adhesion |
| DOI | 10.3892/ol_00000135 |
| 通讯作者 | Ma, yongjie() |
| 英文摘要 | In our previous study, [gd@c-82(oh)(22)](n), a fullerene-based nanoparticle, exhibited potent anti-tumor effects in mouse tumor-bearing models without detectable toxicity the mechanism involved in the anti-tumor effect exerted by [gd@c-82(oh)(22)](n) remains to be elucidated this study found that,n glioblastoma cells treated with [gd@c-82(oh)(22)](n) nanoparticles,n showed a significant impairment in migration and adhesion by cell chemotaxis, scratch and adhesion assays in vitro furthermore, our data showed that the key proteins, cd40 and icam-1, were involved in the inhibition of adhesion in the 22, [gd@c-82(oh)(22)](n) nanoparticle-treated glioblastoma cells,n thus, our study suggests that the [gd@c-82(oh)(22)](n) nanopar, tide is a new potential anti-tumor effector and a therapeutic component for malignant glioblastoma infiltration |
| 收录类别 | SCI |
| WOS关键词 | CONTRAST AGENT ; GLIOMA-CELLS ; IN-VIVO ; METALLOFULLERENES ; EXPRESSION ; REDUCTION ; APOPTOSIS ; INVASION ; ZETA |
| WOS研究方向 | Oncology |
| WOS类目 | Oncology |
| 语种 | 英语 |
| 出版者 | SPANDIDOS PUBL LTD |
| WOS记录号 | WOS:000284800400034 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2175956 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Ma, Yongjie |
| 作者单位 | 1.Tianjin Med Univ, Canc Inst & Hosp, Cent Lab, Dept Oncol, Tianjin 300060, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst High Energy Phys, Lab Bioenvironm Hlth Sci Nanoscale Mat, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jing,Gui, Feng,Ding, Ting,et al. [gd@c-82(oh)(22)](n) nanoparticles inhibit the migration and adhesion of glioblastoma cells[J]. Oncology letters,2010,1(4):771-775. |
| APA | Wang, Jing.,Gui, Feng.,Ding, Ting.,Liu, Xiaoli.,Xing, Gengmei.,...&Ma, Yongjie.(2010).[gd@c-82(oh)(22)](n) nanoparticles inhibit the migration and adhesion of glioblastoma cells.Oncology letters,1(4),771-775. |
| MLA | Wang, Jing,et al."[gd@c-82(oh)(22)](n) nanoparticles inhibit the migration and adhesion of glioblastoma cells".Oncology letters 1.4(2010):771-775. |
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来源：高能物理研究所
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