A naked-eye visible and fluorescence "turn-on'' probe for acetyl-cholinesterase assay and thiols as well as imaging of living cells
文献类型:期刊论文
作者 | Cui, Kai2; Chen, Zhenling1; Wang, Zhuo1; Zhang, Guanxin2; Zhang, Deqing2 |
刊名 | Analyst
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出版日期 | 2011 |
卷号 | 136期号:1页码:191-195 |
ISSN号 | 0003-2654 |
DOI | 10.1039/c0an00456a |
通讯作者 | Wang, zhuo(wangz@nanoctr.cn) |
英文摘要 | A resorufin derivative with a dbs group (probe 1) was designed and investigated for the detection of acetylcholinesterase (ache) and inhibitor screening. the new assay is based on cascade enzymatic and chemical reactions of atc, ache and probe 1, and it can be carried out in a dual-signal detection mode. moreover, the results show that probe 1 can be used for cell fluorescence staining. |
WOS关键词 | INTRAMOLECULAR CHARGE-TRANSFER ; ALZHEIMERS-DISEASE ; ACETYLCHOLINESTERASE ACTIVITY ; ELLMANS REAGENT ; GLUTATHIONE ; HOMOCYSTEINE ; AGGREGATION ; DEMENTIA ; CYSTEINE ; DESIGN |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Analytical |
语种 | 英语 |
WOS记录号 | WOS:000285066000025 |
出版者 | ROYAL SOC CHEMISTRY |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176075 |
专题 | 高能物理研究所 |
通讯作者 | Wang, Zhuo |
作者单位 | 1.CAS Key Lab Biol Effects Nanomat & Nanosafety, Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Organ Solids Lab, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Cui, Kai,Chen, Zhenling,Wang, Zhuo,et al. A naked-eye visible and fluorescence "turn-on'' probe for acetyl-cholinesterase assay and thiols as well as imaging of living cells[J]. Analyst,2011,136(1):191-195. |
APA | Cui, Kai,Chen, Zhenling,Wang, Zhuo,Zhang, Guanxin,&Zhang, Deqing.(2011).A naked-eye visible and fluorescence "turn-on'' probe for acetyl-cholinesterase assay and thiols as well as imaging of living cells.Analyst,136(1),191-195. |
MLA | Cui, Kai,et al."A naked-eye visible and fluorescence "turn-on'' probe for acetyl-cholinesterase assay and thiols as well as imaging of living cells".Analyst 136.1(2011):191-195. |
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来源:高能物理研究所
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