Synchrotron radiation and related nuclear analytical techniques for the study on biological effects of nanomaterials
文献类型：期刊论文
| 作者 | Qu Ying1; Li Yufeng2; Chen Chunying1,2 |
| 刊名 | Progress in chemistry
 |
| 出版日期 | 2011-07-24 |
| 卷号 | 23期号:7页码:1534-1546 |
| 关键词 | Synchrotron radiation X-ray absorption spectroscopy X-ray fluorescence spectroscopy Circular dichroism spectroscopy Nuclear analytical techniques Nanotoxicology Biodistribution |
| ISSN号 | 1005-281X |
| 通讯作者 | Chen chunying(chenchy@nanoctr.cn) |
| 英文摘要 | With the rapid development of nanotechnology,, studies on biological effects of nanomaterials have becoming hotspots. however, the fully understanding of fate and toxicological behavior of nanomaterials as a result of interactions with complex biosystem are highly dependent on the reliable analytical techniques. synchrotron radiation is an advanced light source with notable quality such as high brightness, high level of polarization, high collimation, high brilliance, high intensity and wide tunability in energy/wavelength. it provides particular advantages in elemental mapping and structure characterization of nanomaterials. in this paper, the applications of synchrotron radiation and related nuclear analytical techniques in the studies on the toxicological or biological behaviors of nanomaterials in biological systems are critically reviewed, along with their advantages and limitations. mentioned techniques include synchrotron radiation x ray fluorescence (srxrf), x-ray absorption fine structure (xafs, xanes and exafs), synchrotron radiation circular dichroism spectroscopy (srcd), inductively coupled plasma mass spectrometry (icp-ms), neutron activation analysis (naa), and isotopic tracing. high throughput quantification of nanomaterials can be achieved by icp-ms and naa. the distribution mappings of nanomaterials can be performed by srxrf and isotopic tracing. structural characterization can be acquired by xafs and srcd. all together, these novel techniques will help to lead a better understanding of the biological effects of nanomaterials. |
| WOS关键词 | WALLED CARBON NANOTUBES ; X-RAY-FLUORESCENCE ; TUMOR-BEARING MICE ; IN-VIVO ; ABSORPTION SPECTROSCOPY ; GOLD NANOPARTICLES ; CIRCULAR-DICHROISM ; NASAL INSTILLATION ; TIO2 NANOPARTICLES ; ESCHERICHIA-COLI |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000293676100030 |
| 出版者 | CHINESE ACAD SCIENCES |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176123 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Chen Chunying |
| 作者单位 | 1.Natl Ctr Nanosci & Technol, CAS Key Lab Biomd Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qu Ying,Li Yufeng,Chen Chunying. Synchrotron radiation and related nuclear analytical techniques for the study on biological effects of nanomaterials[J]. Progress in chemistry,2011,23(7):1534-1546. |
| APA | Qu Ying,Li Yufeng,&Chen Chunying.(2011).Synchrotron radiation and related nuclear analytical techniques for the study on biological effects of nanomaterials.Progress in chemistry,23(7),1534-1546. |
| MLA | Qu Ying,et al."Synchrotron radiation and related nuclear analytical techniques for the study on biological effects of nanomaterials".Progress in chemistry 23.7(2011):1534-1546. |
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来源：高能物理研究所
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