Facile fabrication of rare-earth-doped gd2o3 hollow spheres with upconversion luminescence, magnetic resonance, and drug delivery properties
文献类型：期刊论文
| 作者 | Tian, Gan1,3; Gu, Zhanjun1; Liu, Xiaoxiao1; Zhou, Liangjun1; Yin, Wenyan1; Yan, Liang1; Jin, Shan1,4; Ren, Wenlu1; Xing, Gengmei1; Li, Shoujian3 |
| 刊名 | Journal of physical chemistry c
 |
| 出版日期 | 2011-12-08 |
| 卷号 | 115期号:48页码:23790-23796 |
| ISSN号 | 1932-7447 |
| DOI | 10.1021/jp209055t |
| 通讯作者 | Gu, zhanjun(zjgu@ihep.ac.cn) |
| 英文摘要 | Rare-earth (re)-doped gadolinium oxide (gd2o3) hollow nanospheres have been successfully prepared on a large scale via a template-directed method using hydrothermal carbon spheres as sacrificed templates. scanning electron microscope and transmission electron microscope images reveal that these hollow-structured nanosphere spheres have the mesoporous shells that are composed of a large amount of uniform nanoparticles. by doping the re ions (yb/er) into the gd2o3 host matrix, these nps emitted bright multicolored upconversion emissions that can be fine-tuned from green to red by adjusting the codoped yb/er ratio under 980 nm nir laser excitation. the possibility of using these upconversion nanoparticles for optical imaging in vivo has been demonstrated. it was also shown that these gd2o3 nanospheres brightened the t-1-weighted images and enhanced the r(1) relaxivity of water protons, which suggested that they could act as t-1 contrast agents for magnetic resonance (mr) imaging. moreover, these hollow spheres can be used as drug delivery host carriers, and drug storage/release properties were investigated using ibuprofen as the model drug. as a result, the so-prepared nanoscaled gd2o3 hollow spheres bearing upconversion luminescence, mr imaging, and drug delivery capabilities could be potentially employed for simultaneous mr/fluorescent imaging and therapeutic applications. |
| WOS关键词 | SILICA NANOSPHERES ; CONTRAST AGENT ; NANOCRYSTALS ; NANOPARTICLES ; TEMPLATES ; EMISSION ; CARRIERS |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science |
| WOS类目 | Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000297446300020 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176222 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Gu, Zhanjun |
| 作者单位 | 1.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China 2.Natl Ctr Nanosci & Technol China, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Sichuan Univ, Coll Chem, Chengdu 610064, Peoples R China 4.Chinese Acad Sci, Grad Univ, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tian, Gan,Gu, Zhanjun,Liu, Xiaoxiao,et al. Facile fabrication of rare-earth-doped gd2o3 hollow spheres with upconversion luminescence, magnetic resonance, and drug delivery properties[J]. Journal of physical chemistry c,2011,115(48):23790-23796. |
| APA | Tian, Gan.,Gu, Zhanjun.,Liu, Xiaoxiao.,Zhou, Liangjun.,Yin, Wenyan.,...&Zhao, Yuliang.(2011).Facile fabrication of rare-earth-doped gd2o3 hollow spheres with upconversion luminescence, magnetic resonance, and drug delivery properties.Journal of physical chemistry c,115(48),23790-23796. |
| MLA | Tian, Gan,et al."Facile fabrication of rare-earth-doped gd2o3 hollow spheres with upconversion luminescence, magnetic resonance, and drug delivery properties".Journal of physical chemistry c 115.48(2011):23790-23796. |
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